Lactic Acid Extraction and Mass Transfer Characteristics in Slug Flow Capillary Microreactors

Susanti, Jozef G.M. Winkelman, Boelo Schuur, Hero J. Heeres, Jun Yue

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Capillary microreactors operated under the slug flow regime were investigated for the separation of lactic acid from the aqueous phase using liquid–liquid reactive extraction. The experiments were performed at a 1:1 flow ratio of the aqueous to organic phases in a setup consisting of an inlet Y-type mixer connected with a poly(tetrafluoroethylene) capillary microreactor and subsequently an outlet Y-shape phase splitter. The extraction of lactic acid (intake: 0.11 and 0.055 M in water) using 15% (v/v) tri-n-octylamine in n-octanol under ambient conditions approached equilibrium after about 90 s in microreactors without noticeable emulsion formation. The measured reactive extraction performance in microreactors can be well described by a physical mass transfer model according to the penetration theory (developed from a model experimental study for the extraction of acetanilide from water to n-octanol) combined with an instantaneous irreversible reaction assumption.
Original languageEnglish
Pages (from-to)4691-4702
Number of pages12
JournalIndustrial & engineering chemistry research
Issue number16
Publication statusPublished - 2016


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