Laser Doppler perfusion monitoring and imaging: novel approaches

Anne Humeau, Wiendelt Steenbergen, Henrik Nilsson, Tomas Strömberg

Research output: Contribution to journalArticleAcademicpeer-review

119 Citations (Scopus)

Abstract

Laser Doppler flowmetry (LDF) is a non invasive method enabling the monitoring of microvascular blood flow, a very important marker of tissue health. This article gives an overview on the concept of LDF for microvascular perfusion monitoring and imaging. It first describes the theoretical background of the technique. Then, the benefits of LDF signal processing are shown through clinical examples: use of time–frequency representations and wavelets. Afterwards, the paper introduces novel approaches of velocity components. For that purpose, a work providing the determination of the velocities relative contribution in physiologically relevant units (mm/s) is presented. Imaging perfusion is also reviewed through methods based on laser speckle. The most prominent disadvantage of the latter devices being the time needed to produce a perfusion image, solutions are proposed in the last part of the paper.
Original languageUndefined
Pages (from-to)421-435
Number of pages15
JournalMedical & biological engineering & computing
Volume45
Issue number5
DOIs
Publication statusPublished - 2007

Keywords

  • METIS-242439
  • IR-76414

Cite this

Humeau, Anne ; Steenbergen, Wiendelt ; Nilsson, Henrik ; Strömberg, Tomas. / Laser Doppler perfusion monitoring and imaging: novel approaches. In: Medical & biological engineering & computing. 2007 ; Vol. 45, No. 5. pp. 421-435.
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Laser Doppler perfusion monitoring and imaging: novel approaches. / Humeau, Anne; Steenbergen, Wiendelt; Nilsson, Henrik; Strömberg, Tomas.

In: Medical & biological engineering & computing, Vol. 45, No. 5, 2007, p. 421-435.

Research output: Contribution to journalArticleAcademicpeer-review

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T1 - Laser Doppler perfusion monitoring and imaging: novel approaches

AU - Humeau, Anne

AU - Steenbergen, Wiendelt

AU - Nilsson, Henrik

AU - Strömberg, Tomas

PY - 2007

Y1 - 2007

N2 - Laser Doppler flowmetry (LDF) is a non invasive method enabling the monitoring of microvascular blood flow, a very important marker of tissue health. This article gives an overview on the concept of LDF for microvascular perfusion monitoring and imaging. It first describes the theoretical background of the technique. Then, the benefits of LDF signal processing are shown through clinical examples: use of time–frequency representations and wavelets. Afterwards, the paper introduces novel approaches of velocity components. For that purpose, a work providing the determination of the velocities relative contribution in physiologically relevant units (mm/s) is presented. Imaging perfusion is also reviewed through methods based on laser speckle. The most prominent disadvantage of the latter devices being the time needed to produce a perfusion image, solutions are proposed in the last part of the paper.

AB - Laser Doppler flowmetry (LDF) is a non invasive method enabling the monitoring of microvascular blood flow, a very important marker of tissue health. This article gives an overview on the concept of LDF for microvascular perfusion monitoring and imaging. It first describes the theoretical background of the technique. Then, the benefits of LDF signal processing are shown through clinical examples: use of time–frequency representations and wavelets. Afterwards, the paper introduces novel approaches of velocity components. For that purpose, a work providing the determination of the velocities relative contribution in physiologically relevant units (mm/s) is presented. Imaging perfusion is also reviewed through methods based on laser speckle. The most prominent disadvantage of the latter devices being the time needed to produce a perfusion image, solutions are proposed in the last part of the paper.

KW - METIS-242439

KW - IR-76414

U2 - 10.1007/s11517-007-0170-5

DO - 10.1007/s11517-007-0170-5

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JO - Medical & biological engineering & computing

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