Laser speckle contrast analysis for quantifying the Allen test: A feasibility study

Stefan Christiaan Sandker, Erwin Hondebrink, Jan G Grandjean, Wiendelt Steenbergen

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Abstract

Background and Objective The radial artery has become a routinely used conduit for coronary artery bypass graft surgery (CABG). Prior to surgery the Allen test is performed to test the patency of the ulnar artery. A positive Allen test, reperfusion >5 seconds, suggests an insufficient perfusion of the hand by the ulnar artery. In this study we investigated if laser speckle contrast analysis (LASCA) provides an objective determination of the reperfusion time. Materials and Methods When the hand is illuminated with coherent laser light, the backscattered light will result in an interference pattern consisting of bright and dark areas called speckles. This speckle pattern will change due to movement of red blood cells. LASCA uses these changes to visualize the perfusion during the Allen test. Reperfusion is measured on the palmar side of the hand. The reperfusion time is defined as the time from onset of reperfusion to maximum perfusion calculated by a polynomial curve fit. The reperfusion time of the hand of patients undergoing CABG (n = 30) is measured using LASCA and is compared to the conventional Allen test performed by the nurse practitioner. Results LASCA measurements showed a negative Allen test of both hands of 16 patients. Fourteen had a borderline reperfusion time of 5–6 seconds and/or a positive Allen test of one or both hands. No statistical significant difference was observed for the LASCA Allen test compared to the conventional Allen test, P = 0.549 for the left hand and P = 0.223 for the right hand. Conclusion LASCA is able to visualize perfusion of the hand and measure a quick, moderate, slow reperfusion response or no reperfusion. It is technically feasible to determine the reperfusion time of the hand. LASCA can be a useful and objective tool to assess ulnar collateral blood supply to the hand prior to harvesting of the radial artery as a bypass graft
Original languageEnglish
Pages (from-to)186-192
Number of pages7
JournalLasers in surgery and medicine
Volume46
Issue number3
DOIs
Publication statusPublished - 2014

Fingerprint

Feasibility Studies
Reperfusion
Lasers
Hand
Perfusion
Ulnar Artery
Radial Artery
Transplants
Coronary Artery Bypass
Light
Nurse Practitioners
Erythrocytes

Keywords

  • IR-94846
  • METIS-300807

Cite this

@article{fb8aac700984404c902ffa64507224d6,
title = "Laser speckle contrast analysis for quantifying the Allen test: A feasibility study",
abstract = "Background and Objective The radial artery has become a routinely used conduit for coronary artery bypass graft surgery (CABG). Prior to surgery the Allen test is performed to test the patency of the ulnar artery. A positive Allen test, reperfusion >5 seconds, suggests an insufficient perfusion of the hand by the ulnar artery. In this study we investigated if laser speckle contrast analysis (LASCA) provides an objective determination of the reperfusion time. Materials and Methods When the hand is illuminated with coherent laser light, the backscattered light will result in an interference pattern consisting of bright and dark areas called speckles. This speckle pattern will change due to movement of red blood cells. LASCA uses these changes to visualize the perfusion during the Allen test. Reperfusion is measured on the palmar side of the hand. The reperfusion time is defined as the time from onset of reperfusion to maximum perfusion calculated by a polynomial curve fit. The reperfusion time of the hand of patients undergoing CABG (n = 30) is measured using LASCA and is compared to the conventional Allen test performed by the nurse practitioner. Results LASCA measurements showed a negative Allen test of both hands of 16 patients. Fourteen had a borderline reperfusion time of 5–6 seconds and/or a positive Allen test of one or both hands. No statistical significant difference was observed for the LASCA Allen test compared to the conventional Allen test, P = 0.549 for the left hand and P = 0.223 for the right hand. Conclusion LASCA is able to visualize perfusion of the hand and measure a quick, moderate, slow reperfusion response or no reperfusion. It is technically feasible to determine the reperfusion time of the hand. LASCA can be a useful and objective tool to assess ulnar collateral blood supply to the hand prior to harvesting of the radial artery as a bypass graft",
keywords = "IR-94846, METIS-300807",
author = "Sandker, {Stefan Christiaan} and Erwin Hondebrink and Grandjean, {Jan G} and Wiendelt Steenbergen",
year = "2014",
doi = "10.1002/lsm.22213",
language = "English",
volume = "46",
pages = "186--192",
journal = "Lasers in surgery and medicine",
issn = "0196-8092",
publisher = "Wiley-Liss Inc.",
number = "3",

}

Laser speckle contrast analysis for quantifying the Allen test: A feasibility study. / Sandker, Stefan Christiaan; Hondebrink, Erwin; Grandjean, Jan G; Steenbergen, Wiendelt.

In: Lasers in surgery and medicine, Vol. 46, No. 3, 2014, p. 186-192.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Laser speckle contrast analysis for quantifying the Allen test: A feasibility study

AU - Sandker, Stefan Christiaan

AU - Hondebrink, Erwin

AU - Grandjean, Jan G

AU - Steenbergen, Wiendelt

PY - 2014

Y1 - 2014

N2 - Background and Objective The radial artery has become a routinely used conduit for coronary artery bypass graft surgery (CABG). Prior to surgery the Allen test is performed to test the patency of the ulnar artery. A positive Allen test, reperfusion >5 seconds, suggests an insufficient perfusion of the hand by the ulnar artery. In this study we investigated if laser speckle contrast analysis (LASCA) provides an objective determination of the reperfusion time. Materials and Methods When the hand is illuminated with coherent laser light, the backscattered light will result in an interference pattern consisting of bright and dark areas called speckles. This speckle pattern will change due to movement of red blood cells. LASCA uses these changes to visualize the perfusion during the Allen test. Reperfusion is measured on the palmar side of the hand. The reperfusion time is defined as the time from onset of reperfusion to maximum perfusion calculated by a polynomial curve fit. The reperfusion time of the hand of patients undergoing CABG (n = 30) is measured using LASCA and is compared to the conventional Allen test performed by the nurse practitioner. Results LASCA measurements showed a negative Allen test of both hands of 16 patients. Fourteen had a borderline reperfusion time of 5–6 seconds and/or a positive Allen test of one or both hands. No statistical significant difference was observed for the LASCA Allen test compared to the conventional Allen test, P = 0.549 for the left hand and P = 0.223 for the right hand. Conclusion LASCA is able to visualize perfusion of the hand and measure a quick, moderate, slow reperfusion response or no reperfusion. It is technically feasible to determine the reperfusion time of the hand. LASCA can be a useful and objective tool to assess ulnar collateral blood supply to the hand prior to harvesting of the radial artery as a bypass graft

AB - Background and Objective The radial artery has become a routinely used conduit for coronary artery bypass graft surgery (CABG). Prior to surgery the Allen test is performed to test the patency of the ulnar artery. A positive Allen test, reperfusion >5 seconds, suggests an insufficient perfusion of the hand by the ulnar artery. In this study we investigated if laser speckle contrast analysis (LASCA) provides an objective determination of the reperfusion time. Materials and Methods When the hand is illuminated with coherent laser light, the backscattered light will result in an interference pattern consisting of bright and dark areas called speckles. This speckle pattern will change due to movement of red blood cells. LASCA uses these changes to visualize the perfusion during the Allen test. Reperfusion is measured on the palmar side of the hand. The reperfusion time is defined as the time from onset of reperfusion to maximum perfusion calculated by a polynomial curve fit. The reperfusion time of the hand of patients undergoing CABG (n = 30) is measured using LASCA and is compared to the conventional Allen test performed by the nurse practitioner. Results LASCA measurements showed a negative Allen test of both hands of 16 patients. Fourteen had a borderline reperfusion time of 5–6 seconds and/or a positive Allen test of one or both hands. No statistical significant difference was observed for the LASCA Allen test compared to the conventional Allen test, P = 0.549 for the left hand and P = 0.223 for the right hand. Conclusion LASCA is able to visualize perfusion of the hand and measure a quick, moderate, slow reperfusion response or no reperfusion. It is technically feasible to determine the reperfusion time of the hand. LASCA can be a useful and objective tool to assess ulnar collateral blood supply to the hand prior to harvesting of the radial artery as a bypass graft

KW - IR-94846

KW - METIS-300807

U2 - 10.1002/lsm.22213

DO - 10.1002/lsm.22213

M3 - Article

VL - 46

SP - 186

EP - 192

JO - Lasers in surgery and medicine

JF - Lasers in surgery and medicine

SN - 0196-8092

IS - 3

ER -