Laser speckle contrast imaging: theoretical and practical limitations

David Briers, David D. Duncan, Evan Hirst, Sean J. Kirkpatrick, Marcus Larsson, Wiendelt Steenbergen, Tomas Stromberg, Oliver B. Thompson

Research output: Contribution to journalArticleAcademicpeer-review

376 Citations (Scopus)
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When laser light illuminates a diffuse object, it produces a random interference effect known as a speckle pattern. If there is movement in the object, the speckles fluctuate in intensity. These fluctuations can provide information about the movement. A simple way of accessing this information is to image the speckle pattern with an exposure time longer than the shortest speckle fluctuation time scale—the fluctuations cause a blurring of the speckle, leading to a reduction in the local speckle contrast. Thus, velocity distributions are coded as speckle contrast variations. The same information can be obtained by using the Doppler effect, but producing a two-dimensional Doppler map requires either scanning of the laser beam or imaging with a high-speed camera: laser speckle contrast imaging (LSCI) avoids the need to scan and can be performed with a normal CCD- or CMOS-camera. LSCI is used primarily to map flow systems, especially blood flow. The development of LSCI is reviewed and its limitations and problems are investigated
Original languageEnglish
Pages (from-to)066018-1-066018-9
Number of pages9
JournalJournal of biomedical optics
Issue number6
Publication statusPublished - 2013


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