Latency dependent development of related firing patterns of cultured cortical neurons

Jakob le Feber, Jaap van Pelt, Wim Rutten

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

    3 Citations (Scopus)

    Abstract

    Networks of cortical neurons were grown over multi electrode arrays to enable simultaneous measurement of signals from multiple neurons. We described functional connectivity in these networks by relationships be¬tween individual electrodes, based on conditional firing probabilities. In this study we investigated periods in which the strength of a relation¬ship monotonously increased (strengthening) or decreased (weakening) during periods of 24 or 10 hours. We observed a slightly increased incidence of latencies up to 25 ms during strengthening, while these latencies rarely occurreded during weakening. Next, it appeared that relationships tended to strengthen more than average in periods with latencies in the range 5-30 ms, whereas strengthening was significantly less than average in latencies 40-65 ms.
    Original languageUndefined
    Title of host publication29th annual international conference of the IEEE EMBS
    Place of PublicationUK
    PublisherIOP Publishing
    Pages3000-3003
    Number of pages4
    ISBN (Print)1-4244-0788-5
    DOIs
    Publication statusPublished - Aug 2007
    Event29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2007 - Convention Center, 'Cité Internationale', Lyon, France
    Duration: 23 Aug 200726 Aug 2017
    Conference number: 29

    Publication series

    Name
    PublisherIOP Publishing
    NumberPaper P-NS

    Conference

    Conference29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2007
    Abbreviated titleEMBC
    CountryFrance
    CityLyon
    Period23/08/0726/08/17

    Keywords

    • BSS-Neurotechnology and cellular engineering
    • METIS-245768
    • EWI-11372
    • IR-62012

    Cite this

    le Feber, J., van Pelt, J., & Rutten, W. (2007). Latency dependent development of related firing patterns of cultured cortical neurons. In 29th annual international conference of the IEEE EMBS (pp. 3000-3003). UK: IOP Publishing. https://doi.org/10.1109/IEMBS.2007.4352960