Learning in Live Neuronal Cultures: a Training Protocol Evaluated

Jakob le Feber; J. Stegenga; Wim Rutten

Learning in Live Neuronal Cultures: a Training Protocol Evaluated

Jakob le Feber, J. Stegenga, Wim Rutten

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

Abstract

We applied a training protocol to cultured cortical networks, adapted from Shahaf and Marom [1]. Like they did, on average we found an improved response to input stimuli. However, not all experiments were successful, and the shapes of our learning curves differed from theirs. Furthermore, we investi-gated connectivity changes in the whole network. We concluded that not only a selected connection could be altered, but that connectivity in the rest of the networks also changed. Connectivity changes may go undetected if general parameters like network wide firing rate are used to analyze connectivity.

Original language	Undefined
Title of host publication	6th International Meeting on Substrate-Integrated Microelectrodes
Place of Publication	Stuttgart
Publisher	BIOPRO
Pages	65-66
Number of pages	2
ISBN (Print)	3-938345-05-5
Publication status	Published - 8 Jul 2008
Event	6th international meeting on substrate-integrated micro electrode arrays 2008 - Stuttgart, Germany Duration: 8 Jul 2008 → 11 Jul 2008 Conference number: 6

Publication series

Name
Publisher	Biopro
Number	WoTUG-31
Volume	5

Conference

Conference	6th international meeting on substrate-integrated micro electrode arrays 2008
Country/Territory	Germany
City	Stuttgart
Period	8/07/08 → 11/07/08

Keywords

EWI-14263
BSS-Neurotechnology and cellular engineering
IR-62571
METIS-254929

Access to Document

http://eprints.eemcs.utwente.nl/secure2/14263/01/lefeber_learning_in_live.pdf

Cite this

@inproceedings{99141fe46ed24f408f71dbd75f7c1c0b,

title = "Learning in Live Neuronal Cultures: a Training Protocol Evaluated",

abstract = "We applied a training protocol to cultured cortical networks, adapted from Shahaf and Marom [1]. Like they did, on average we found an improved response to input stimuli. However, not all experiments were successful, and the shapes of our learning curves differed from theirs. Furthermore, we investi-gated connectivity changes in the whole network. We concluded that not only a selected connection could be altered, but that connectivity in the rest of the networks also changed. Connectivity changes may go undetected if general parameters like network wide firing rate are used to analyze connectivity.",

keywords = "EWI-14263, BSS-Neurotechnology and cellular engineering, IR-62571, METIS-254929",

author = "{le Feber}, Jakob and J. Stegenga and Wim Rutten",

note = "http://www.nmi.de/meameeting2008/; 6th international meeting on substrate-integrated micro electrode arrays 2008 ; Conference date: 08-07-2008 Through 11-07-2008",

year = "2008",

month = jul,

day = "8",

language = "Undefined",

isbn = "3-938345-05-5",

publisher = "BIOPRO",

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booktitle = "6th International Meeting on Substrate-Integrated Microelectrodes",

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le Feber, J, Stegenga, J & Rutten, W 2008, Learning in Live Neuronal Cultures: a Training Protocol Evaluated. in 6th International Meeting on Substrate-Integrated Microelectrodes. BIOPRO, Stuttgart, pp. 65-66, 6th international meeting on substrate-integrated micro electrode arrays 2008, Stuttgart, Germany, 8/07/08. <http://eprints.eemcs.utwente.nl/secure2/14263/01/lefeber_learning_in_live.pdf>

TY - GEN

T1 - Learning in Live Neuronal Cultures: a Training Protocol Evaluated

AU - le Feber, Jakob

AU - Stegenga, J.

AU - Rutten, Wim

N1 - Conference code: 6

PY - 2008/7/8

Y1 - 2008/7/8

N2 - We applied a training protocol to cultured cortical networks, adapted from Shahaf and Marom [1]. Like they did, on average we found an improved response to input stimuli. However, not all experiments were successful, and the shapes of our learning curves differed from theirs. Furthermore, we investi-gated connectivity changes in the whole network. We concluded that not only a selected connection could be altered, but that connectivity in the rest of the networks also changed. Connectivity changes may go undetected if general parameters like network wide firing rate are used to analyze connectivity.

AB - We applied a training protocol to cultured cortical networks, adapted from Shahaf and Marom [1]. Like they did, on average we found an improved response to input stimuli. However, not all experiments were successful, and the shapes of our learning curves differed from theirs. Furthermore, we investi-gated connectivity changes in the whole network. We concluded that not only a selected connection could be altered, but that connectivity in the rest of the networks also changed. Connectivity changes may go undetected if general parameters like network wide firing rate are used to analyze connectivity.

KW - EWI-14263

KW - BSS-Neurotechnology and cellular engineering

KW - IR-62571

KW - METIS-254929

M3 - Conference contribution

SN - 3-938345-05-5

SP - 65

EP - 66

BT - 6th International Meeting on Substrate-Integrated Microelectrodes

PB - BIOPRO

CY - Stuttgart

T2 - 6th international meeting on substrate-integrated micro electrode arrays 2008

Y2 - 8 July 2008 through 11 July 2008

ER -