Life-like motion driven by artificial molecular machines

Federico Lancia, Alexander Ryabchun, Nathalie Katsonis*

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

7 Citations (Scopus)

Abstract

Essentially, all motion in living organisms emerges from the collective action of biological molecular machines transforming chemical energy, originally harvested from light, into ordered activity. As a man-made counterpart to nature’s biomolecular machines, chemists have created artificial molecular machines that display controlled and even directional motion in response to light. However, to be of practical value, the motion of these light-fuelled molecular machines will have to be coupled to the rest of the world. Inspired by the complex functional movement seen in the plant and animal world, chemists have undertaken the challenge to harness molecular motion and, so, they have set artificial molecular motors and switches to work and perform useful mechanical action at the macroscopic level. Here, we review these recent developments. We show how modern research has embraced the full complexity of the molecular world by aiming at the design of autonomous, and sometimes adaptive, molecular systems that work continuously under the effect of illumination. We report evidence that molecular motion can be engineered into highly sophisticated movements and that, from a fundamental point of view, continuous movement can only emerge when man-made molecules cooperate, in space and time. Eventually, unravelling the rules of molecular motion will support the creation of molecular materials that produce work continuously under a constant input of energy.

Original languageEnglish
Pages (from-to)536-551
Number of pages16
JournalNature Reviews Chemistry
Volume3
Issue number9
DOIs
Publication statusPublished - 1 Sep 2019

Fingerprint

Animals
Lighting
Switches
Molecules

Cite this

@article{0935527fea3a4d50b2580f884e67105d,
title = "Life-like motion driven by artificial molecular machines",
abstract = "Essentially, all motion in living organisms emerges from the collective action of biological molecular machines transforming chemical energy, originally harvested from light, into ordered activity. As a man-made counterpart to nature’s biomolecular machines, chemists have created artificial molecular machines that display controlled and even directional motion in response to light. However, to be of practical value, the motion of these light-fuelled molecular machines will have to be coupled to the rest of the world. Inspired by the complex functional movement seen in the plant and animal world, chemists have undertaken the challenge to harness molecular motion and, so, they have set artificial molecular motors and switches to work and perform useful mechanical action at the macroscopic level. Here, we review these recent developments. We show how modern research has embraced the full complexity of the molecular world by aiming at the design of autonomous, and sometimes adaptive, molecular systems that work continuously under the effect of illumination. We report evidence that molecular motion can be engineered into highly sophisticated movements and that, from a fundamental point of view, continuous movement can only emerge when man-made molecules cooperate, in space and time. Eventually, unravelling the rules of molecular motion will support the creation of molecular materials that produce work continuously under a constant input of energy.",
author = "Federico Lancia and Alexander Ryabchun and Nathalie Katsonis",
year = "2019",
month = "9",
day = "1",
doi = "10.1038/s41570-019-0122-2",
language = "English",
volume = "3",
pages = "536--551",
journal = "Nature Reviews Chemistry",
issn = "2397-3358",
publisher = "Nature Publishing Group",
number = "9",

}

Life-like motion driven by artificial molecular machines. / Lancia, Federico; Ryabchun, Alexander; Katsonis, Nathalie.

In: Nature Reviews Chemistry, Vol. 3, No. 9, 01.09.2019, p. 536-551.

Research output: Contribution to journalReview articleAcademicpeer-review

TY - JOUR

T1 - Life-like motion driven by artificial molecular machines

AU - Lancia, Federico

AU - Ryabchun, Alexander

AU - Katsonis, Nathalie

PY - 2019/9/1

Y1 - 2019/9/1

N2 - Essentially, all motion in living organisms emerges from the collective action of biological molecular machines transforming chemical energy, originally harvested from light, into ordered activity. As a man-made counterpart to nature’s biomolecular machines, chemists have created artificial molecular machines that display controlled and even directional motion in response to light. However, to be of practical value, the motion of these light-fuelled molecular machines will have to be coupled to the rest of the world. Inspired by the complex functional movement seen in the plant and animal world, chemists have undertaken the challenge to harness molecular motion and, so, they have set artificial molecular motors and switches to work and perform useful mechanical action at the macroscopic level. Here, we review these recent developments. We show how modern research has embraced the full complexity of the molecular world by aiming at the design of autonomous, and sometimes adaptive, molecular systems that work continuously under the effect of illumination. We report evidence that molecular motion can be engineered into highly sophisticated movements and that, from a fundamental point of view, continuous movement can only emerge when man-made molecules cooperate, in space and time. Eventually, unravelling the rules of molecular motion will support the creation of molecular materials that produce work continuously under a constant input of energy.

AB - Essentially, all motion in living organisms emerges from the collective action of biological molecular machines transforming chemical energy, originally harvested from light, into ordered activity. As a man-made counterpart to nature’s biomolecular machines, chemists have created artificial molecular machines that display controlled and even directional motion in response to light. However, to be of practical value, the motion of these light-fuelled molecular machines will have to be coupled to the rest of the world. Inspired by the complex functional movement seen in the plant and animal world, chemists have undertaken the challenge to harness molecular motion and, so, they have set artificial molecular motors and switches to work and perform useful mechanical action at the macroscopic level. Here, we review these recent developments. We show how modern research has embraced the full complexity of the molecular world by aiming at the design of autonomous, and sometimes adaptive, molecular systems that work continuously under the effect of illumination. We report evidence that molecular motion can be engineered into highly sophisticated movements and that, from a fundamental point of view, continuous movement can only emerge when man-made molecules cooperate, in space and time. Eventually, unravelling the rules of molecular motion will support the creation of molecular materials that produce work continuously under a constant input of energy.

UR - http://www.scopus.com/inward/record.url?scp=85070814903&partnerID=8YFLogxK

U2 - 10.1038/s41570-019-0122-2

DO - 10.1038/s41570-019-0122-2

M3 - Review article

AN - SCOPUS:85070814903

VL - 3

SP - 536

EP - 551

JO - Nature Reviews Chemistry

JF - Nature Reviews Chemistry

SN - 2397-3358

IS - 9

ER -