The combination of optical coherence tomography and spectroscopy may allow for highly localized, quantitative measurements of tissue spectral properties. We present, for the first time to our knowledge, quantitative measurements of the absorption coefficients of phantoms and of hemoglobin and oxygenated hemoglobin with spectroscopic optical coherence tomography (SOCT). Our results suggest that SOCT will be able to provide localized, quantitative oxygenation measurements.
Faber, D. J., Mik, E. G., Aalders, M. C. G., & van Leeuwen, T. (2003). Light absorption of (oxy-)hemoglobin assessed by spectroscopic optical coherence tomography. Optics letters, 28(16), 1436-1438. https://doi.org/10.1364/OL.28.001436