TY - JOUR
T1 - Lignin-based non-crosslinked nanocarriers
T2 - A promising delivery system of pesticide for development of sustainable agriculture
AU - Liang, Wenlong
AU - Zhang, Jiadong
AU - Wurm, Frederik R.
AU - Wang, Rong
AU - Cheng, Jingli
AU - Xie, Zhengang
AU - Li, Xianbin
AU - Zhao, Jinhao
N1 - Funding Information:
This work was financially supported by the National Natural Science Foundation of China (No. 31872022 ), the Public Welfare Technology Application Research Project of Zhejiang Province Analysis and Testing Project (No. LGC22C140001 ), and The Science and Technology Project of Zhejiang Province (No. 2021C02045 and 2021C02010 ). Thanks to the research group of Chuanqing Zhang at Zhejiang A&F University for their help on the Colletotrichum gloeosporioides.
Publisher Copyright:
© 2022
PY - 2022/11/1
Y1 - 2022/11/1
N2 - Lignin sulfonate (LS), a waste material from the paper pulping, was modified with benzoic anhydride to obtain benzoylated lignin sulfonates of adjustable hydrophilicity (BLS). When BLS was combined with difenoconazole (Di), a broad-spectrum fungicide, lignin-based, non-crosslinked nanoparticles were obtained either by solvent exchange or solvent evaporation. When a mass ratio of 1:5 LS: benzoic anhydride was used, the Di release from Di@BLS5 after 1248 h was ca. 74 %, while a commercial difenoconazole microemulsion (Di ME) reached 100 % already after 96 h, proving the sustained release from the lignin nanocarriers. The formulation of Di in lignin-based nanocarriers also improved the UV stability and the foliar retention of Di compared to the commercial formulation of the fungicide. Bioactivity assay showed that Di@BLS5 exhibited high activities and duration against strawberry anthracnose (Colletotrichum gloeosporioides). Overall, the construction of fungicide delivery nano-platform using BLS via a simple non-crosslinked approach is a novel and promising way to develop new formulations for nanopesticide and the development of sustainable agriculture.
AB - Lignin sulfonate (LS), a waste material from the paper pulping, was modified with benzoic anhydride to obtain benzoylated lignin sulfonates of adjustable hydrophilicity (BLS). When BLS was combined with difenoconazole (Di), a broad-spectrum fungicide, lignin-based, non-crosslinked nanoparticles were obtained either by solvent exchange or solvent evaporation. When a mass ratio of 1:5 LS: benzoic anhydride was used, the Di release from Di@BLS5 after 1248 h was ca. 74 %, while a commercial difenoconazole microemulsion (Di ME) reached 100 % already after 96 h, proving the sustained release from the lignin nanocarriers. The formulation of Di in lignin-based nanocarriers also improved the UV stability and the foliar retention of Di compared to the commercial formulation of the fungicide. Bioactivity assay showed that Di@BLS5 exhibited high activities and duration against strawberry anthracnose (Colletotrichum gloeosporioides). Overall, the construction of fungicide delivery nano-platform using BLS via a simple non-crosslinked approach is a novel and promising way to develop new formulations for nanopesticide and the development of sustainable agriculture.
KW - Controlled release
KW - Crop protection
KW - Lignin
KW - Nanopesticide
KW - Sustainable agriculture
KW - 22/4 OA procedure
UR - http://www.scopus.com/inward/record.url?scp=85136117001&partnerID=8YFLogxK
U2 - 10.1016/j.ijbiomac.2022.08.103
DO - 10.1016/j.ijbiomac.2022.08.103
M3 - Article
C2 - 35987356
AN - SCOPUS:85136117001
SN - 0141-8130
VL - 220
SP - 472
EP - 481
JO - International journal of biological macromolecules
JF - International journal of biological macromolecules
ER -
