LIPID-POLYMER-CONJUGATES COMPOSITIONS COMPRISING CORTICOSTEROIDS FOR THE TREATMENT OF CANCER

Raymond M. Schiffelers (Inventor), J.M. Metselaar (Inventor), Grietje Molema (Inventor), Gerrit Storm, (Inventor)

    Research output: Patent

    Abstract

    The use of long-circulating colloidal carrier compositions comprising a corticosteroid and a lipid-polymer-conjugate, wherein the polymer is a poly((derivatised) amino acid) and optionally a further useful active ingredient, for the manufacture of a medicament useful in the treatment of non-lymphatic cancer and especially of solid (non-haematological) malignancies and metastases (solid primary and secondary tumors) is provided. Also provided are long-circulating colloidal carrier compositions comprising a corticosteroid in combination with a further drug or active ingredient that enhances the beneficial effect shown by the corticosteroid alone.

    Original languageEnglish
    Patent numberWO2004019914
    IPCA61K 31/ 727 A I
    Priority date27/08/02
    Publication statusPublished - 11 Mar 2004

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