Lipid-polymer-conjugates compositions comprising corticosteroids for the treatment of cancer

Raymond M. Schiffelers (Inventor), Josbert M. Metselaar (Inventor), Grietje Molema (Inventor), Gerrit Storm, (Inventor)

Research output: Patent

Abstract

The use of long-circulating colloidal carrier compositions comprising a corticosteroid and a lipid-polymer-conjugate, wherein the polymer is a poly((derivatised) amino acid) and optionally a further useful active ingredient, for the manufacture of a medicament useful in the treatment of non-lymphatic cancer and especially of solid (non-haematological) malignancies and metastases (solid primary and secondary tumors) is provided. Also provided are long-circulating colloidal carrier compositions comprising a corticosteroid in combination with a further drug or active ingredient that enhances the beneficial effect shown by the corticosteroid alone.

Original languageEnglish
Patent numberWO2004019914
IPCA61K 31/ 727 A I
Priority date27/08/02
Publication statusPublished - 11 Mar 2004

Fingerprint

Dive into the research topics of 'Lipid-polymer-conjugates compositions comprising corticosteroids for the treatment of cancer'. Together they form a unique fingerprint.

Cite this