Localization Study of Co-Phthalocyanines in Cells by Raman Micro(spectro)scopy

S.Y. Arzhantsev; S.Y. Arzhantsev; A.Y. Chikishev; A.Y. Chikishev; N.I. Koroteev; Jan Greve; Cornelis Otto; N.M. Sijtsema

Localization Study of Co-Phthalocyanines in Cells by Raman Micro(spectro)scopy

S.Y. Arzhantsev, S.Y. Arzhantsev, A.Y. Chikishev, A.Y. Chikishev, N.I. Koroteev, Jan Greve, Cornelis Otto, N.M. Sijtsema

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Abstract

An investigation of intracellular localization of Co-phthalocyanines is reported. The Raman images of K562 cells stained with phthalocyanine were acquired. To understand the peculiarities of the Raman images, measurements were performed at different z-axis positions. The intracellular concentration of phthalocyanine was estimated. A colocalization study was carried out using the fluorescence probes FITC-dextran and acridine orange by means of Raman and fluorescence microscopy. Partial colocalization with both probes was revealed.

Original language	Undefined
Pages (from-to)	205-208
Number of pages	4
Journal	Journal of raman spectroscopy
Volume	30
Issue number	3
Publication status	Published - 1999

Keywords

METIS-128412
IR-71537

Access to Document

http://www3.interscience.wiley.com/journal/60500864/abstract

Cite this

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title = "Localization Study of Co-Phthalocyanines in Cells by Raman Micro(spectro)scopy",

abstract = "An investigation of intracellular localization of Co-phthalocyanines is reported. The Raman images of K562 cells stained with phthalocyanine were acquired. To understand the peculiarities of the Raman images, measurements were performed at different z-axis positions. The intracellular concentration of phthalocyanine was estimated. A colocalization study was carried out using the fluorescence probes FITC-dextran and acridine orange by means of Raman and fluorescence microscopy. Partial colocalization with both probes was revealed.",

keywords = "METIS-128412, IR-71537",

author = "S.Y. Arzhantsev and S.Y. Arzhantsev and A.Y. Chikishev and A.Y. Chikishev and N.I. Koroteev and Jan Greve and Cornelis Otto and N.M. Sijtsema",

year = "1999",

language = "Undefined",

volume = "30",

pages = "205--208",

journal = "Journal of raman spectroscopy",

issn = "0377-0486",

publisher = "Wiley",

number = "3",

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TY - JOUR

T1 - Localization Study of Co-Phthalocyanines in Cells by Raman Micro(spectro)scopy

AU - Arzhantsev, S.Y.

AU - Chikishev, A.Y.

AU - Koroteev, N.I.

AU - Greve, Jan

AU - Otto, Cornelis

AU - Sijtsema, N.M.

PY - 1999

Y1 - 1999

N2 - An investigation of intracellular localization of Co-phthalocyanines is reported. The Raman images of K562 cells stained with phthalocyanine were acquired. To understand the peculiarities of the Raman images, measurements were performed at different z-axis positions. The intracellular concentration of phthalocyanine was estimated. A colocalization study was carried out using the fluorescence probes FITC-dextran and acridine orange by means of Raman and fluorescence microscopy. Partial colocalization with both probes was revealed.

AB - An investigation of intracellular localization of Co-phthalocyanines is reported. The Raman images of K562 cells stained with phthalocyanine were acquired. To understand the peculiarities of the Raman images, measurements were performed at different z-axis positions. The intracellular concentration of phthalocyanine was estimated. A colocalization study was carried out using the fluorescence probes FITC-dextran and acridine orange by means of Raman and fluorescence microscopy. Partial colocalization with both probes was revealed.

KW - METIS-128412

KW - IR-71537

M3 - Article

SN - 0377-0486

VL - 30

SP - 205

EP - 208

JO - Journal of raman spectroscopy

JF - Journal of raman spectroscopy

IS - 3

ER -