Lyme arthritis in the Netherlands: A nationwide survey among rheumatologists

I. Blaauw, L. Nohlmans, E. van den Berg-Loonen, J. Rasker, S. van der Linden

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A nationwide survey among all 118 Dutch rheumatologists (response rate 85%) yielded 42 patients with Lyme arthritis. The arthritis was nonpersistent in all these patients. A tick bite was reported by 23 of these 42 patients (55%). Erythema migrans was recalled by 19 patients (45%). Cardiac manifestations occurred in 4 patients (9%) and neurologic symptoms in 14 patients (33%). By immunoabsorbent assay or immunofluorescence technique 37 patients (88%) had positive IgG antibodies to Borrelia burgdorferi. The distribution of HLA-DR alleles of 28 of these patients was not different from the healthy population. The response to antibiotic treatment was considered good in 34 patients (81%). The clinical features of the Dutch patients with Lyme arthritis closely resemble the description of the disease reported from the United States.

Original languageEnglish
Pages (from-to)1819-1822
Number of pages4
JournalJournal of rheumatology
Issue number12
Publication statusPublished - 1 Dec 1991
Externally publishedYes


  • HLA-DR antigens
  • Lyme arthritis
  • Lyme borreliosis
  • Lyme disease
  • Prevalence
  • Survey


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