Abstract
Original language | English |
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Title of host publication | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences |
Place of Publication | Basel, Switzerland |
Publisher | Chemical and Biological Micro Systems Society |
Pages | 1664-1665 |
Number of pages | 2 |
Edition | 23 |
ISBN (Electronic) | 978-1-7334190-0-0 |
Publication status | Published - 28 Oct 2019 |
Event | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2019 - Congress Center Basel, Basel, Switzerland Duration: 27 Oct 2019 → 31 Oct 2019 Conference number: 23 https://cbmsociety.org/microtas/microtas2019/ |
Conference
Conference | 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2019 |
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Abbreviated title | MicroTAS 2019 |
Country | Switzerland |
City | Basel |
Period | 27/10/19 → 31/10/19 |
Internet address |
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Macro valve and peristaltic pump with cleanroom-free fabrication for multiplexed organ-on-chip applications. / Bossink, Elsbeth G.B.M.; Vollertsen, Anke R.; Segerink, Loes I.; Odijk, Mathieu .
23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences. 23. ed. Basel, Switzerland : Chemical and Biological Micro Systems Society, 2019. p. 1664-1665.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review
TY - GEN
T1 - Macro valve and peristaltic pump with cleanroom-free fabrication for multiplexed organ-on-chip applications
AU - Bossink, Elsbeth G.B.M.
AU - Vollertsen, Anke R.
AU - Segerink, Loes I.
AU - Odijk, Mathieu
PY - 2019/10/28
Y1 - 2019/10/28
N2 - Integrated microfluidic valves enable automated control in microfluidic systems as they can be applied for mixing, pumping, and compartmentalisation purposes. However, many organ-on-chip systems require channel dimensions in the range of hundreds of micrometres while the typical fabrication process for normally open micro valves requires a reflow photoresist which is not capable of achieving these dimensions. Here we show a mechanical macro valve, fabricated cleanroom-free by micromilling, closing and bridging a 400 μm high, 1000 μm wide channel. Furthermore, we use the valves to create an inlet switch and a peristaltic pump with a pumping rate of 2 μL/min.
AB - Integrated microfluidic valves enable automated control in microfluidic systems as they can be applied for mixing, pumping, and compartmentalisation purposes. However, many organ-on-chip systems require channel dimensions in the range of hundreds of micrometres while the typical fabrication process for normally open micro valves requires a reflow photoresist which is not capable of achieving these dimensions. Here we show a mechanical macro valve, fabricated cleanroom-free by micromilling, closing and bridging a 400 μm high, 1000 μm wide channel. Furthermore, we use the valves to create an inlet switch and a peristaltic pump with a pumping rate of 2 μL/min.
M3 - Conference contribution
SP - 1664
EP - 1665
BT - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences
PB - Chemical and Biological Micro Systems Society
CY - Basel, Switzerland
ER -