Magnetic Particle Spectrometry of Fe3O4 Multi-granule Nanoclusters

Lijun Pan, Bum Chul Park, Michael Ledwig, Leon Abelmann, Young Keun Kim

    Research output: Contribution to journalArticleAcademicpeer-review

    2 Citations (Scopus)

    Abstract

    Magnetic particle imaging (MPI) is a novel high-resolution medical imaging method that does not use ionizing radiation, but safe iron-oxide nanoparticles as contrast agents. By employing magnetite (Fe3O4) multi-granule nanoclusters (MGNCs), one has two control parameters: the diameter of the particles and that of granules in single particles. Here we investigate the effect of the size of the particles at constant granule size, as well as the effect of granule size at constant particle size on the magnetization reversal. Saturation magnetization Ms value increases with increasing granule diameter and particle diameter while the coercivity Hc value reaches a maximum at a particle size of about 60 nm. MGNCs with an average particle size of 77 nm and granule diameter of 17 nm show larger response in the higher harmonics compared to the commercial reference, FeraSpin R dispersion, both at 20 and 30 mT. This result demonstrates that the MGNC concept allows tailoring of the magnetic properties of the particles to the imaging conditions in MPI.
    Original languageEnglish
    Article number5101004
    Number of pages4
    JournalIEEE transactions on magnetics
    Volume53
    Issue number11
    DOIs
    Publication statusPublished - 1 Nov 2017

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