Managing complexity: model-building in systems biology and its challenges for philosophy of science

    Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

    Abstract

    In the history of science there have been many conceptual crossings between the bios and téchne realms, as researchers have sought to use biology to inspire design or represent biology in terms of mechanical models. Philosophers have been comfortable describing the analogical relationships and their limitations between technological devices and biological organisms, and setting up the boundaries between them. However, technology and computational simulation are creating new interactions and fusions between bios and téchne in emergent quantitative biological elds like synthetic biology, systems biology and bioengineering that extend to practices of investigation themselves. Technology and the quantitative perspective that comes with it have become means of structuring both scienti c practice and scienti c understanding in novel ways that can address biological complexity .
    Original languageEnglish
    Title of host publicationThe Future of Scientific Practice: Bio-Techno-Logos
    EditorsMarta Bertalaso
    Place of PublicationLondon
    PublisherRoutledge Taylor & Francis Group
    Chapter5
    Number of pages20
    ISBN (Electronic)9781317316848
    ISBN (Print)9781848935624
    Publication statusPublished - 2015

    Publication series

    NameHistory and philosophy of technoscience

    Fingerprint

    Philosophy of Science
    Systems Biology
    History of the Sciences
    Fusion
    Synthetic Biology
    Organism
    Computational Simulation
    Philosopher
    Interaction

    Cite this

    MacLeod, M. A. J. (2015). Managing complexity: model-building in systems biology and its challenges for philosophy of science. In M. Bertalaso (Ed.), The Future of Scientific Practice: Bio-Techno-Logos (History and philosophy of technoscience). London: Routledge Taylor & Francis Group.
    MacLeod, Miles Alexander James. / Managing complexity: model-building in systems biology and its challenges for philosophy of science. The Future of Scientific Practice: Bio-Techno-Logos. editor / Marta Bertalaso. London : Routledge Taylor & Francis Group, 2015. (History and philosophy of technoscience).
    @inbook{f30fdc2309b740f9b8dfc04648c78e27,
    title = "Managing complexity: model-building in systems biology and its challenges for philosophy of science",
    abstract = "In the history of science there have been many conceptual crossings between the bios and t{\'e}chne realms, as researchers have sought to use biology to inspire design or represent biology in terms of mechanical models. Philosophers have been comfortable describing the analogical relationships and their limitations between technological devices and biological organisms, and setting up the boundaries between them. However, technology and computational simulation are creating new interactions and fusions between bios and t{\'e}chne in emergent quantitative biological elds like synthetic biology, systems biology and bioengineering that extend to practices of investigation themselves. Technology and the quantitative perspective that comes with it have become means of structuring both scienti c practice and scienti c understanding in novel ways that can address biological complexity .",
    author = "MacLeod, {Miles Alexander James}",
    year = "2015",
    language = "English",
    isbn = "9781848935624",
    series = "History and philosophy of technoscience",
    publisher = "Routledge Taylor & Francis Group",
    editor = "Marta Bertalaso",
    booktitle = "The Future of Scientific Practice: Bio-Techno-Logos",
    address = "United Kingdom",

    }

    MacLeod, MAJ 2015, Managing complexity: model-building in systems biology and its challenges for philosophy of science. in M Bertalaso (ed.), The Future of Scientific Practice: Bio-Techno-Logos. History and philosophy of technoscience, Routledge Taylor & Francis Group, London.

    Managing complexity: model-building in systems biology and its challenges for philosophy of science. / MacLeod, Miles Alexander James.

    The Future of Scientific Practice: Bio-Techno-Logos. ed. / Marta Bertalaso. London : Routledge Taylor & Francis Group, 2015. (History and philosophy of technoscience).

    Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

    TY - CHAP

    T1 - Managing complexity: model-building in systems biology and its challenges for philosophy of science

    AU - MacLeod, Miles Alexander James

    PY - 2015

    Y1 - 2015

    N2 - In the history of science there have been many conceptual crossings between the bios and téchne realms, as researchers have sought to use biology to inspire design or represent biology in terms of mechanical models. Philosophers have been comfortable describing the analogical relationships and their limitations between technological devices and biological organisms, and setting up the boundaries between them. However, technology and computational simulation are creating new interactions and fusions between bios and téchne in emergent quantitative biological elds like synthetic biology, systems biology and bioengineering that extend to practices of investigation themselves. Technology and the quantitative perspective that comes with it have become means of structuring both scienti c practice and scienti c understanding in novel ways that can address biological complexity .

    AB - In the history of science there have been many conceptual crossings between the bios and téchne realms, as researchers have sought to use biology to inspire design or represent biology in terms of mechanical models. Philosophers have been comfortable describing the analogical relationships and their limitations between technological devices and biological organisms, and setting up the boundaries between them. However, technology and computational simulation are creating new interactions and fusions between bios and téchne in emergent quantitative biological elds like synthetic biology, systems biology and bioengineering that extend to practices of investigation themselves. Technology and the quantitative perspective that comes with it have become means of structuring both scienti c practice and scienti c understanding in novel ways that can address biological complexity .

    M3 - Chapter

    SN - 9781848935624

    T3 - History and philosophy of technoscience

    BT - The Future of Scientific Practice: Bio-Techno-Logos

    A2 - Bertalaso, Marta

    PB - Routledge Taylor & Francis Group

    CY - London

    ER -

    MacLeod MAJ. Managing complexity: model-building in systems biology and its challenges for philosophy of science. In Bertalaso M, editor, The Future of Scientific Practice: Bio-Techno-Logos. London: Routledge Taylor & Francis Group. 2015. (History and philosophy of technoscience).