Measurement of biofilm growth and local hydrodynamics using optical coherence tomography

Nicolas Weiss; Khalid El Tayeb El Obied; Jeroen Kalkman; Rob G.H. Lammertink; Ton G. van Leeuwen

doi:10.1364/BOE.7.003508

Measurement of biofilm growth and local hydrodynamics using optical coherence tomography

Nicolas Weiss, Khalid El Tayeb El Obied, Jeroen Kalkman, Rob G.H. Lammertink, Ton G. van Leeuwen

Research output: Contribution to journal › Article › Academic › peer-review

16 Citations (Scopus)

131 Downloads (Pure)

Abstract

We report on localized and simultaneous measurement of biofilm growth and local hydrodynamics in a microfluidic channel using optical coherence tomography. We measure independently with high spatio-temporal resolution the longitudinal flow velocity component parallel to the imaging beam and the transverse flow velocity component perpendicular to the imaging beam. Based on the measured velocities we calculate the shear-rates in the flow channel. We show the relation between the measured biofilm structure and flow velocities as biofilm growth progresses over the course of 48 hours

Original language	English
Pages (from-to)	3508-3518
Journal	Biomedical optics express
Volume	7
Issue number	9
DOIs	https://doi.org/10.1364/BOE.7.003508
Publication status	Published - 2016

Access to Document

10.1364/BOE.7.003508

ArticleFinal published version, 2.85 MB

Cite this

@article{e8f59c86175342f6a77843e3e8febb24,

title = "Measurement of biofilm growth and local hydrodynamics using optical coherence tomography",

abstract = "We report on localized and simultaneous measurement of biofilm growth and local hydrodynamics in a microfluidic channel using optical coherence tomography. We measure independently with high spatio-temporal resolution the longitudinal flow velocity component parallel to the imaging beam and the transverse flow velocity component perpendicular to the imaging beam. Based on the measured velocities we calculate the shear-rates in the flow channel. We show the relation between the measured biofilm structure and flow velocities as biofilm growth progresses over the course of 48 hours",

author = "Nicolas Weiss and {El Tayeb El Obied}, Khalid and Jeroen Kalkman and Lammertink, {Rob G.H.} and {van Leeuwen}, {Ton G.}",

year = "2016",

doi = "10.1364/BOE.7.003508",

language = "English",

volume = "7",

pages = "3508--3518",

journal = "Biomedical optics express",

issn = "2156-7085",

publisher = "The Optical Society",

number = "9",

}

TY - JOUR

T1 - Measurement of biofilm growth and local hydrodynamics using optical coherence tomography

AU - Weiss, Nicolas

AU - El Tayeb El Obied, Khalid

AU - Kalkman, Jeroen

AU - Lammertink, Rob G.H.

AU - van Leeuwen, Ton G.

PY - 2016

Y1 - 2016

N2 - We report on localized and simultaneous measurement of biofilm growth and local hydrodynamics in a microfluidic channel using optical coherence tomography. We measure independently with high spatio-temporal resolution the longitudinal flow velocity component parallel to the imaging beam and the transverse flow velocity component perpendicular to the imaging beam. Based on the measured velocities we calculate the shear-rates in the flow channel. We show the relation between the measured biofilm structure and flow velocities as biofilm growth progresses over the course of 48 hours

AB - We report on localized and simultaneous measurement of biofilm growth and local hydrodynamics in a microfluidic channel using optical coherence tomography. We measure independently with high spatio-temporal resolution the longitudinal flow velocity component parallel to the imaging beam and the transverse flow velocity component perpendicular to the imaging beam. Based on the measured velocities we calculate the shear-rates in the flow channel. We show the relation between the measured biofilm structure and flow velocities as biofilm growth progresses over the course of 48 hours

U2 - 10.1364/BOE.7.003508

DO - 10.1364/BOE.7.003508

M3 - Article

SN - 2156-7085

VL - 7

SP - 3508

EP - 3518

JO - Biomedical optics express

JF - Biomedical optics express

IS - 9

ER -

Measurement of biofilm growth and local hydrodynamics using optical coherence tomography

Abstract

Access to Document

Fingerprint

Cite this