Mechanism and echo time dependence of the fast response in fMR

Rosemary C. Dymond; David G. Norris

doi:10.1002/mrm.1910380102

Mechanism and echo time dependence of the fast response in fMR

Rosemary C. Dymond^*, David G. Norris

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

6 Citations (Scopus)

2 Downloads (Pure)

Abstract

The fast response (FR) is an early reduction in the amplitude of the fMR signal occurring shortly after the onset of stimulation. Owing to its potential advantages in terms of temporal and spatial resolution, it may be of considerable significance in functional experiments. A model for the mechanism of the FR was developed which accounts for the fMRS finding that the amplitude of the dip decreases with increasing echo time. Two computer simulations that confirmed the predictions of the model and showed that it is possible to select optimal echo times for the detection of the FR were performed.

Original language	English
Pages (from-to)	1-6
Number of pages	6
Journal	Magnetic resonance in medicine
Volume	38
Issue number	1
DOIs	https://doi.org/10.1002/mrm.1910380102
Publication status	Published - Jul 1997
Externally published	Yes

Keywords

Cortical activation
Deoxyhemoglobin
Fast response
Functional spectroscopy

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Magnetic Resonance in Med - 2005 - DymondFinal published version, 556 KB

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abstract = "The fast response (FR) is an early reduction in the amplitude of the fMR signal occurring shortly after the onset of stimulation. Owing to its potential advantages in terms of temporal and spatial resolution, it may be of considerable significance in functional experiments. A model for the mechanism of the FR was developed which accounts for the fMRS finding that the amplitude of the dip decreases with increasing echo time. Two computer simulations that confirmed the predictions of the model and showed that it is possible to select optimal echo times for the detection of the FR were performed.",

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AU - Norris, David G.

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AB - The fast response (FR) is an early reduction in the amplitude of the fMR signal occurring shortly after the onset of stimulation. Owing to its potential advantages in terms of temporal and spatial resolution, it may be of considerable significance in functional experiments. A model for the mechanism of the FR was developed which accounts for the fMRS finding that the amplitude of the dip decreases with increasing echo time. Two computer simulations that confirmed the predictions of the model and showed that it is possible to select optimal echo times for the detection of the FR were performed.

KW - Cortical activation

KW - Deoxyhemoglobin

KW - Fast response

KW - Functional spectroscopy

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ER -

Mechanism and echo time dependence of the fast response in fMR

Abstract

Keywords

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