Membrane adsorbers: development and applications

Maria Elena Avramescu

Membrane adsorbers: development and applications

Maria Elena Avramescu

Membrane Science and Technology

Research output: Thesis › PhD Thesis - Research UT, graduation UT

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Abstract

Bioaffinity separation principally asks for membranes that show a good compatibility to the targeted biological fluids, provide coupling sites for (bio)ligands and posses a hydrophilic surface to reduce non-specific adsorption caused by hydrophobic atraction. Due to its good blood compatibility and very low water solubility, ethylene vinyl alcohol copolymers(EVAL) has become a promising biomedical membrane material, but has so far not been investigated in detail for (bio)affinity separation. The work reported in this thesis focuses on the preparation of EVAL microporous membrane adsorbers for protein separation based on affinity or ion exchange interaction modes.

Original language	English
Awarding Institution	University of Twente
Supervisors/Advisors	Wessling, Matthias , Supervisor Sager, W.F.C., Co-Supervisor
Award date	19 Dec 2002
Place of Publication	Enschede
Publisher	University of Twente
Print ISBNs	978-90-365-1838-3
Publication status	Published - 19 Dec 2002

Keywords

IR-75156

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title = "Membrane adsorbers: development and applications",

abstract = "Bioaffinity separation principally asks for membranes that show a good compatibility to the targeted biological fluids, provide coupling sites for (bio)ligands and posses a hydrophilic surface to reduce non-specific adsorption caused by hydrophobic atraction. Due to its good blood compatibility and very low water solubility, ethylene vinyl alcohol copolymers(EVAL) has become a promising biomedical membrane material, but has so far not been investigated in detail for (bio)affinity separation. The work reported in this thesis focuses on the preparation of EVAL microporous membrane adsorbers for protein separation based on affinity or ion exchange interaction modes.",

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AB - Bioaffinity separation principally asks for membranes that show a good compatibility to the targeted biological fluids, provide coupling sites for (bio)ligands and posses a hydrophilic surface to reduce non-specific adsorption caused by hydrophobic atraction. Due to its good blood compatibility and very low water solubility, ethylene vinyl alcohol copolymers(EVAL) has become a promising biomedical membrane material, but has so far not been investigated in detail for (bio)affinity separation. The work reported in this thesis focuses on the preparation of EVAL microporous membrane adsorbers for protein separation based on affinity or ion exchange interaction modes.

KW - IR-75156

M3 - PhD Thesis - Research UT, graduation UT

SN - 978-90-365-1838-3

PB - University of Twente

CY - Enschede

ER -

Membrane adsorbers: development and applications

Abstract

Keywords

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