Metal complexation by tripodal N-Acyl(thio)urea and picolin(thio)amide compounds: synthesis/extraction and potentiometric studies

M.M. Reinoso garcia, Arjan Dijkman, Willem Verboom, David Reinhoudt, Elzbieta Malinowska, Dorota Wojciechowska, Mariusz Pietrzak, Pavel Selucky

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The synthesis and binding properties towards different cations of a series of tripodal ligands functionalized with N-acyl(thio)urea and picolin(thio)amide moieties are described. For the extraction of Am3+ and Eu3+ the compounds are not efficient. However, N-acylurea derivative 10 exhibit a significant selectivity for Am3+ over Eu3+. Upon addition of the synergistic hexabrominated bis(dicarbollide)cobalt anion (Br6-COSAN) the distribution coefficients for Am3+ and Eu3+ increase up to 1000 for picolinamide derivative 11. Extraction studies with metal picrates (Pb2+, Cu2+, Ag+, Hg2+, Cd2+, Eu3+, Fe3+, K+, Na+, and Ca2+) or the incorporation in ion selective electrodes (ISEs), show that picolinamide derivative 11 is a very selective and strong ionophore for Hg2+ and that N-acylthiourea 8 is a very good ionophore for Ag+.
Original languageUndefined
Pages (from-to)2131-2138
JournalEuropean journal of organic chemistry
Issue number10
Publication statusPublished - 2005


  • METIS-225079
  • IR-52996

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