Metal–Organic Frameworks (MOFs) as Multivalent Materials: Size Control and Surface Functionalization by Monovalent Capping Ligands

Timon Rijnaarts, R. Weinhart-Mejia, Richard J.M. Egberink, W.P.E. van Roosmalen, Jurriaan Huskens

Research output: Contribution to journalArticleAcademicpeer-review

21 Citations (Scopus)

Abstract

Control over particle size and composition are pivotal to tune the properties of metal organic frameworks (MOFs), for example, for biomedical applications. Particle-size control and functionalization of MIL-88A were achieved by using stoichiometric replacement of a small fraction of the divalent fumarate by monovalent capping ligands. A fluorine-capping ligand was used to quantify the surface coverage of capping ligand at the surface of MIL-88A. Size control at the nanoscale was achieved by using a monovalent carboxylic acid-functionalized poly(ethylene glycol) (PEG-COOH) ligand at different concentrations. Finally, a biotin–carboxylic acid capping ligand was used to functionalize MIL-88A to bind fluorescently labeled streptavidin as an example towards bioapplications.
Original languageUndefined
Pages (from-to)10296-10301
Number of pages6
JournalChemistry: a European journal
Volume21
Issue number29
DOIs
Publication statusPublished - 2015

Keywords

  • METIS-314622
  • IR-99882

Cite this

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abstract = "Control over particle size and composition are pivotal to tune the properties of metal organic frameworks (MOFs), for example, for biomedical applications. Particle-size control and functionalization of MIL-88A were achieved by using stoichiometric replacement of a small fraction of the divalent fumarate by monovalent capping ligands. A fluorine-capping ligand was used to quantify the surface coverage of capping ligand at the surface of MIL-88A. Size control at the nanoscale was achieved by using a monovalent carboxylic acid-functionalized poly(ethylene glycol) (PEG-COOH) ligand at different concentrations. Finally, a biotin–carboxylic acid capping ligand was used to functionalize MIL-88A to bind fluorescently labeled streptavidin as an example towards bioapplications.",
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Metal–Organic Frameworks (MOFs) as Multivalent Materials: Size Control and Surface Functionalization by Monovalent Capping Ligands. / Rijnaarts, Timon; Weinhart-Mejia, R.; Egberink, Richard J.M.; van Roosmalen, W.P.E.; Huskens, Jurriaan.

In: Chemistry: a European journal, Vol. 21, No. 29, 2015, p. 10296-10301.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Metal–Organic Frameworks (MOFs) as Multivalent Materials: Size Control and Surface Functionalization by Monovalent Capping Ligands

AU - Rijnaarts, Timon

AU - Weinhart-Mejia, R.

AU - Egberink, Richard J.M.

AU - van Roosmalen, W.P.E.

AU - Huskens, Jurriaan

PY - 2015

Y1 - 2015

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AB - Control over particle size and composition are pivotal to tune the properties of metal organic frameworks (MOFs), for example, for biomedical applications. Particle-size control and functionalization of MIL-88A were achieved by using stoichiometric replacement of a small fraction of the divalent fumarate by monovalent capping ligands. A fluorine-capping ligand was used to quantify the surface coverage of capping ligand at the surface of MIL-88A. Size control at the nanoscale was achieved by using a monovalent carboxylic acid-functionalized poly(ethylene glycol) (PEG-COOH) ligand at different concentrations. Finally, a biotin–carboxylic acid capping ligand was used to functionalize MIL-88A to bind fluorescently labeled streptavidin as an example towards bioapplications.

KW - METIS-314622

KW - IR-99882

U2 - 10.1002/chem.201501974

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SP - 10296

EP - 10301

JO - Chemistry: a European journal

JF - Chemistry: a European journal

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