Methodology for the qualitative screening of parallel arrays of potential Am3+ ligands using a photographic film

H.H. Dam, Tanja Tomasberger, David Reinhoudt, Willem Verboom

Research output: Contribution to journalArticleAcademicpeer-review


A screening method for parallel Am3+ ligand libraries is presented. The method makes use of α-radiation in combination with a photographic film to detect the complexed Am3+. After screening and development of the film spots of varying intensities are obtained. The intensities of the spots correspond with the amount of complexed Am3+. This allows a fast discrimination between the Am3+ complexation efficiencies of ligands from large libraries. Depending on the exposure time of the film, activities as small as 5 Bq 241Am can be detected. Using internal standards a semi-quantitative assessment can be performed.
Original languageUndefined
Pages (from-to)79-83
Number of pages5
JournalAnalytica chimica acta
Issue number1
Publication statusPublished - 2009


  • Actinides
  • Am3+ ligand
  • Combinatorial
  • Library screening
  • Photographic film
  • METIS-263197
  • IR-79111

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