Abstract
A screening method for parallel Am3+ ligand libraries is presented. The method makes use of α-radiation in combination with a photographic film to detect the complexed Am3+. After screening and development of the film spots of varying intensities are obtained. The intensities of the spots correspond with the amount of complexed Am3+. This allows a fast discrimination between the Am3+ complexation efficiencies of ligands from large libraries. Depending on the exposure time of the film, activities as small as 5 Bq 241Am can be detected. Using internal standards a semi-quantitative assessment can be performed.
Original language | Undefined |
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Pages (from-to) | 79-83 |
Number of pages | 5 |
Journal | Analytica chimica acta |
Volume | 635 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2009 |
Keywords
- Actinides
- Am3+ ligand
- Combinatorial
- Library screening
- Photographic film
- METIS-263197
- IR-79111