Micro Total Analysis Systems: Microfluidic aspects, integration concept and applications

    Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

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    Abstract

    In this contribution three aspects of miniaturized total analysis systems (µTAS) are described and discussed in detail. First, an overview of microfabricated components for fluid handling is given. A description of the importance of sampling- and fluid-handling techniques is followed by details of microvalves, micropumps and micro flowchannels. Secondly, the problems associated with system integration are discussed. As a solution for the realization of microfluidic- and micro analysis systems, the concept of a planar mixed circuit board (MCB) as a platform for the integration of different components is described. In addition, the design, modeling and simulation, and realization of several components in the form of standard modules for integration on a MCB is described. As an illustration of the potential of this approach, the realization of a µTAS demonstrator for the optical detection of the pH change of a pH indicator, is presented. Finally, a number of different applications of µTAS are described, such as on-line process monitoring, environmental monitoring, biomedical and space applications and DNA-analysis.
    Original languageUndefined
    Title of host publicationTopics in Current Chemestry
    Place of PublicationBerlin
    PublisherSpringer
    Pages21-49
    ISBN (Print)9783540634249
    DOIs
    Publication statusPublished - 1997

    Publication series

    Name
    PublisherSpringer verlag

    Keywords

    • METIS-112475
    • Microsystem - (bio)chemical analysis - fluid handling - µTAS - micropump
    • IR-15593

    Cite this

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    title = "Micro Total Analysis Systems: Microfluidic aspects, integration concept and applications",
    abstract = "In this contribution three aspects of miniaturized total analysis systems (µTAS) are described and discussed in detail. First, an overview of microfabricated components for fluid handling is given. A description of the importance of sampling- and fluid-handling techniques is followed by details of microvalves, micropumps and micro flowchannels. Secondly, the problems associated with system integration are discussed. As a solution for the realization of microfluidic- and micro analysis systems, the concept of a planar mixed circuit board (MCB) as a platform for the integration of different components is described. In addition, the design, modeling and simulation, and realization of several components in the form of standard modules for integration on a MCB is described. As an illustration of the potential of this approach, the realization of a µTAS demonstrator for the optical detection of the pH change of a pH indicator, is presented. Finally, a number of different applications of µTAS are described, such as on-line process monitoring, environmental monitoring, biomedical and space applications and DNA-analysis.",
    keywords = "METIS-112475, Microsystem - (bio)chemical analysis - fluid handling - µTAS - micropump, IR-15593",
    author = "{van den Berg}, Albert and Lammerink, {Theodorus S.J.}",
    note = "Topics in Current Chemistry 194",
    year = "1997",
    doi = "10.1007/3-540-69544-3_2",
    language = "Undefined",
    isbn = "9783540634249",
    publisher = "Springer",
    pages = "21--49",
    booktitle = "Topics in Current Chemestry",

    }

    Micro Total Analysis Systems: Microfluidic aspects, integration concept and applications. / van den Berg, Albert; Lammerink, Theodorus S.J.

    Topics in Current Chemestry. Berlin : Springer, 1997. p. 21-49.

    Research output: Chapter in Book/Report/Conference proceedingChapterAcademic

    TY - CHAP

    T1 - Micro Total Analysis Systems: Microfluidic aspects, integration concept and applications

    AU - van den Berg, Albert

    AU - Lammerink, Theodorus S.J.

    N1 - Topics in Current Chemistry 194

    PY - 1997

    Y1 - 1997

    N2 - In this contribution three aspects of miniaturized total analysis systems (µTAS) are described and discussed in detail. First, an overview of microfabricated components for fluid handling is given. A description of the importance of sampling- and fluid-handling techniques is followed by details of microvalves, micropumps and micro flowchannels. Secondly, the problems associated with system integration are discussed. As a solution for the realization of microfluidic- and micro analysis systems, the concept of a planar mixed circuit board (MCB) as a platform for the integration of different components is described. In addition, the design, modeling and simulation, and realization of several components in the form of standard modules for integration on a MCB is described. As an illustration of the potential of this approach, the realization of a µTAS demonstrator for the optical detection of the pH change of a pH indicator, is presented. Finally, a number of different applications of µTAS are described, such as on-line process monitoring, environmental monitoring, biomedical and space applications and DNA-analysis.

    AB - In this contribution three aspects of miniaturized total analysis systems (µTAS) are described and discussed in detail. First, an overview of microfabricated components for fluid handling is given. A description of the importance of sampling- and fluid-handling techniques is followed by details of microvalves, micropumps and micro flowchannels. Secondly, the problems associated with system integration are discussed. As a solution for the realization of microfluidic- and micro analysis systems, the concept of a planar mixed circuit board (MCB) as a platform for the integration of different components is described. In addition, the design, modeling and simulation, and realization of several components in the form of standard modules for integration on a MCB is described. As an illustration of the potential of this approach, the realization of a µTAS demonstrator for the optical detection of the pH change of a pH indicator, is presented. Finally, a number of different applications of µTAS are described, such as on-line process monitoring, environmental monitoring, biomedical and space applications and DNA-analysis.

    KW - METIS-112475

    KW - Microsystem - (bio)chemical analysis - fluid handling - µTAS - micropump

    KW - IR-15593

    U2 - 10.1007/3-540-69544-3_2

    DO - 10.1007/3-540-69544-3_2

    M3 - Chapter

    SN - 9783540634249

    SP - 21

    EP - 49

    BT - Topics in Current Chemestry

    PB - Springer

    CY - Berlin

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