Microfluidic-based detection platform for on-the-flow analyte characterization

Peter Kiesel, Markus Beck, Noble Johnson, Michael Bassler

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Abstract

While commercial flow cytometers are sophisticated analytical instruments extensively used in research and clinical laboratories, they do not meet the challenging practical requirements for point-of-care (POC) diagnostics. In this paper we will describe and illustrate a new detection technique that will enable a compact, microfluidic-based flow cytometer that satisfies POC specifications for performance, robustness, compactness, cost, reagent consumption, and ease of use. The technology has been demonstrated with CD4 counts in whole blood.
Original languageEnglish
Article number760608
JournalProceedings of SPIE - the international society for optical engineering
Volume7606
DOIs
Publication statusPublished - 2010
Externally publishedYes

Keywords

  • flow cytometer
  • opto-fluidics
  • on-the-flow analyte characterization
  • micro-fluidics

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