Microfluidic devices as gas – Ionic liquid membrane contactors for CO2 removal from anaesthesia gases

M. Malankowska, C.F. Martins, H.S. Rho, L.A. Neves, R.M. Tiggelaar, João G. Crespo, M.P. Pina (Corresponding Author), R. Mallada, H. Gardeniers, I.M. Coelhoso (Corresponding Author)

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)

Abstract

This work proposes a microfluidic gas – ionic liquid contactor for CO2 removal from anaesthesia gas, containing Xe. The working principle involves the transport of CO2 through a polymer flat membrane followed by its capture and enzymatic bioconversion in the ionic liquid solvent. Microfluidic devices enable a rapid and inexpensive screening of potential CO2 absorbers. The alveolar – type design of the ionic liquid chamber was adopted to reduce mass transfer limitations of CO2 through the liquid phase. Polydimethylsiloxane (PDMS) was the chosen polymer for dense membrane, as well as for the microfluidic device fabrication, mainly due to the high permeability of gases, O2 and CO2, and low cost. The selected ionic liquid was cholinium propionate (CP) with a water activity of 0.753, due to its high affinity towards CO2 and biocompatibility with the enzyme used for CO2 conversion to bicarbonate, carbonic anhydrase (CA). The CO2 and Xe permeability and CO2/Xe selectivity were determined in the microfluidic devices developed and compared to those exhibited by free standing PDMS membranes mounted on a standard permeation cell. The performance of the microfluidic devices as gas – ionic liquid contactors was evaluated for a given solvent flow rate with pure gas streams of CO2 and Xe. The obtained results show that cholinium propionate with or without the enzyme has no effect on the Xe transport, but remarkably enhances the affinity towards carbon dioxide leading to enhancement factor up to 1.9 in the presence of 0.1 mg CA/gIL.

Original languageEnglish
Pages (from-to)107-115
Number of pages9
JournalJournal of membrane science
Volume545
DOIs
Publication statusPublished - 1 Jan 2018

Fingerprint

Lab-On-A-Chip Devices
contactors
anesthesia
Ionic Liquids
Liquid membranes
microfluidic devices
Ionic liquids
Microfluidics
Anesthesia
Gases
membranes
Membranes
Carbonic anhydrase
carbonic anhydrase
liquids
gases
Carbonic Anhydrases
Propionates
Polydimethylsiloxane
affinity

Keywords

  • Carbon dioxide removal
  • Carbonic anhydrase enzyme
  • Cholinium-based ionic liquids
  • Microfluidic membrane contactor
  • Anaesthesia gas recovery

Cite this

Malankowska, M., Martins, C. F., Rho, H. S., Neves, L. A., Tiggelaar, R. M., Crespo, J. G., ... Coelhoso, I. M. (2018). Microfluidic devices as gas – Ionic liquid membrane contactors for CO2 removal from anaesthesia gases. Journal of membrane science, 545, 107-115. https://doi.org/10.1016/j.memsci.2017.09.065
Malankowska, M. ; Martins, C.F. ; Rho, H.S. ; Neves, L.A. ; Tiggelaar, R.M. ; Crespo, João G. ; Pina, M.P. ; Mallada, R. ; Gardeniers, H. ; Coelhoso, I.M. / Microfluidic devices as gas – Ionic liquid membrane contactors for CO2 removal from anaesthesia gases. In: Journal of membrane science. 2018 ; Vol. 545. pp. 107-115.
@article{264ea4dc75fd43eeae70ef30e5f7d76a,
title = "Microfluidic devices as gas – Ionic liquid membrane contactors for CO2 removal from anaesthesia gases",
abstract = "This work proposes a microfluidic gas – ionic liquid contactor for CO2 removal from anaesthesia gas, containing Xe. The working principle involves the transport of CO2 through a polymer flat membrane followed by its capture and enzymatic bioconversion in the ionic liquid solvent. Microfluidic devices enable a rapid and inexpensive screening of potential CO2 absorbers. The alveolar – type design of the ionic liquid chamber was adopted to reduce mass transfer limitations of CO2 through the liquid phase. Polydimethylsiloxane (PDMS) was the chosen polymer for dense membrane, as well as for the microfluidic device fabrication, mainly due to the high permeability of gases, O2 and CO2, and low cost. The selected ionic liquid was cholinium propionate (CP) with a water activity of 0.753, due to its high affinity towards CO2 and biocompatibility with the enzyme used for CO2 conversion to bicarbonate, carbonic anhydrase (CA). The CO2 and Xe permeability and CO2/Xe selectivity were determined in the microfluidic devices developed and compared to those exhibited by free standing PDMS membranes mounted on a standard permeation cell. The performance of the microfluidic devices as gas – ionic liquid contactors was evaluated for a given solvent flow rate with pure gas streams of CO2 and Xe. The obtained results show that cholinium propionate with or without the enzyme has no effect on the Xe transport, but remarkably enhances the affinity towards carbon dioxide leading to enhancement factor up to 1.9 in the presence of 0.1 mg CA/gIL.",
keywords = "Carbon dioxide removal, Carbonic anhydrase enzyme, Cholinium-based ionic liquids, Microfluidic membrane contactor, Anaesthesia gas recovery",
author = "M. Malankowska and C.F. Martins and H.S. Rho and L.A. Neves and R.M. Tiggelaar and Crespo, {Jo{\~a}o G.} and M.P. Pina and R. Mallada and H. Gardeniers and I.M. Coelhoso",
year = "2018",
month = "1",
day = "1",
doi = "10.1016/j.memsci.2017.09.065",
language = "English",
volume = "545",
pages = "107--115",
journal = "Journal of membrane science",
issn = "0376-7388",
publisher = "Elsevier",

}

Malankowska, M, Martins, CF, Rho, HS, Neves, LA, Tiggelaar, RM, Crespo, JG, Pina, MP, Mallada, R, Gardeniers, H & Coelhoso, IM 2018, 'Microfluidic devices as gas – Ionic liquid membrane contactors for CO2 removal from anaesthesia gases' Journal of membrane science, vol. 545, pp. 107-115. https://doi.org/10.1016/j.memsci.2017.09.065

Microfluidic devices as gas – Ionic liquid membrane contactors for CO2 removal from anaesthesia gases. / Malankowska, M.; Martins, C.F.; Rho, H.S.; Neves, L.A.; Tiggelaar, R.M.; Crespo, João G.; Pina, M.P. (Corresponding Author); Mallada, R.; Gardeniers, H.; Coelhoso, I.M. (Corresponding Author).

In: Journal of membrane science, Vol. 545, 01.01.2018, p. 107-115.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Microfluidic devices as gas – Ionic liquid membrane contactors for CO2 removal from anaesthesia gases

AU - Malankowska, M.

AU - Martins, C.F.

AU - Rho, H.S.

AU - Neves, L.A.

AU - Tiggelaar, R.M.

AU - Crespo, João G.

AU - Pina, M.P.

AU - Mallada, R.

AU - Gardeniers, H.

AU - Coelhoso, I.M.

PY - 2018/1/1

Y1 - 2018/1/1

N2 - This work proposes a microfluidic gas – ionic liquid contactor for CO2 removal from anaesthesia gas, containing Xe. The working principle involves the transport of CO2 through a polymer flat membrane followed by its capture and enzymatic bioconversion in the ionic liquid solvent. Microfluidic devices enable a rapid and inexpensive screening of potential CO2 absorbers. The alveolar – type design of the ionic liquid chamber was adopted to reduce mass transfer limitations of CO2 through the liquid phase. Polydimethylsiloxane (PDMS) was the chosen polymer for dense membrane, as well as for the microfluidic device fabrication, mainly due to the high permeability of gases, O2 and CO2, and low cost. The selected ionic liquid was cholinium propionate (CP) with a water activity of 0.753, due to its high affinity towards CO2 and biocompatibility with the enzyme used for CO2 conversion to bicarbonate, carbonic anhydrase (CA). The CO2 and Xe permeability and CO2/Xe selectivity were determined in the microfluidic devices developed and compared to those exhibited by free standing PDMS membranes mounted on a standard permeation cell. The performance of the microfluidic devices as gas – ionic liquid contactors was evaluated for a given solvent flow rate with pure gas streams of CO2 and Xe. The obtained results show that cholinium propionate with or without the enzyme has no effect on the Xe transport, but remarkably enhances the affinity towards carbon dioxide leading to enhancement factor up to 1.9 in the presence of 0.1 mg CA/gIL.

AB - This work proposes a microfluidic gas – ionic liquid contactor for CO2 removal from anaesthesia gas, containing Xe. The working principle involves the transport of CO2 through a polymer flat membrane followed by its capture and enzymatic bioconversion in the ionic liquid solvent. Microfluidic devices enable a rapid and inexpensive screening of potential CO2 absorbers. The alveolar – type design of the ionic liquid chamber was adopted to reduce mass transfer limitations of CO2 through the liquid phase. Polydimethylsiloxane (PDMS) was the chosen polymer for dense membrane, as well as for the microfluidic device fabrication, mainly due to the high permeability of gases, O2 and CO2, and low cost. The selected ionic liquid was cholinium propionate (CP) with a water activity of 0.753, due to its high affinity towards CO2 and biocompatibility with the enzyme used for CO2 conversion to bicarbonate, carbonic anhydrase (CA). The CO2 and Xe permeability and CO2/Xe selectivity were determined in the microfluidic devices developed and compared to those exhibited by free standing PDMS membranes mounted on a standard permeation cell. The performance of the microfluidic devices as gas – ionic liquid contactors was evaluated for a given solvent flow rate with pure gas streams of CO2 and Xe. The obtained results show that cholinium propionate with or without the enzyme has no effect on the Xe transport, but remarkably enhances the affinity towards carbon dioxide leading to enhancement factor up to 1.9 in the presence of 0.1 mg CA/gIL.

KW - Carbon dioxide removal

KW - Carbonic anhydrase enzyme

KW - Cholinium-based ionic liquids

KW - Microfluidic membrane contactor

KW - Anaesthesia gas recovery

UR - http://www.scopus.com/inward/record.url?scp=85030163914&partnerID=8YFLogxK

U2 - 10.1016/j.memsci.2017.09.065

DO - 10.1016/j.memsci.2017.09.065

M3 - Article

VL - 545

SP - 107

EP - 115

JO - Journal of membrane science

JF - Journal of membrane science

SN - 0376-7388

ER -