Microfluidic platform for the simultaneous generation of four independent gradients: towards the high throughput screening of trace elements for bone tissue engineering

Björn Harink, Séverine le Gac, Clemens van Blitterswijk, Pamela Habibovic

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

    9 Downloads (Pure)

    Abstract

    We propose a microfluidics-based cell-culture platform for the screening of trace elements in bone tissue engineering. With this platform, it is possible to create four stable, independent and perpendicular diffusion-based concentration gradients in a single square chamber, in which cells are cultured. This allows examining the combined effect of four compounds in a single assay.
    Original languageEnglish
    Title of host publication14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
    EditorsSabeth Verpoorte, Helen Andersson-Svahn, Jenny Emnéus, Nicole Pamme
    PublisherThe Chemical and Biological Microsystems Society
    Pages638-640
    ISBN (Print)978-0-9798064-3-8
    Publication statusPublished - 2010
    Event14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, µTAS 2010 - Groningen, Netherlands
    Duration: 3 Oct 20107 Oct 2010
    Conference number: 14

    Publication series

    NameInternational Conference on Miniaterized Systems for Chemistry and Life Sciences : [proceedings]
    PublisherThe Chemical and Biological Microsystems Society
    Volume2010
    ISSN (Print)1556-5904

    Conference

    Conference14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, µTAS 2010
    Abbreviated titleMicroTAS
    CountryNetherlands
    CityGroningen
    Period3/10/107/10/10

    Keywords

    • Gradient
    • Trace element
    • Bone
    • Tissue engineering

    Fingerprint Dive into the research topics of 'Microfluidic platform for the simultaneous generation of four independent gradients: towards the high throughput screening of trace elements for bone tissue engineering'. Together they form a unique fingerprint.

    Cite this