Micromolding of solvent resistant microfluidic devices,

Theodorus J.A. Renckens, Dainius Janeliunas, Hilbert van Vliet, Jan H. van Esch, Guido Mul, Michiel T. Kreutzer

Research output: Contribution to journalArticleAcademicpeer-review

23 Citations (Scopus)

Abstract

We demonstrate a rapid fabrication procedure for solvent-resistant microfluidic devices based on the perfluoropolyether (PFPE) SIFEL. We carefully modified the poly-dimethylsiloxane (PDMS) micromolding procedure, such that it can still be executed using the standard facilities for PDMS devices. Most importantly, devices with a thin SIFEL layer for the patterned channels and a PDMS support layer on top offered the best of two worlds in terms of chemical and mechanical stability during fabrication and use. Tests revealed that these devices overcome two important drawbacks of PDMS devices: (i) incompatibility with almost all non-aqueous solvents, and (ii) leaching of oligomer into solution. The potential of our device is shown by performing a relevant organic synthesis reaction with aggressive reactants and solvents. PFPE-PDMS devices will greatly expand the application window of micromolded devices
Original languageEnglish
Pages (from-to)2035-2038
Number of pages4
JournalLab on a chip
Volume11
Issue number12
DOIs
Publication statusPublished - 2011

Keywords

  • IR-95301
  • METIS-280311

Fingerprint Dive into the research topics of 'Micromolding of solvent resistant microfluidic devices,'. Together they form a unique fingerprint.

Cite this