Microtechnologies and nanotechnologies for single-cell analysis

Helene Andersson, Albert van den Berg

    Research output: Contribution to journalArticleAcademicpeer-review

    164 Citations (Scopus)

    Abstract

    Many efforts are currently underway to try and mimic the properties of single cells with the aim of designing chips that are as efficient as cells. However, cells are nature’s nanotechnology engineering at the scale of atoms and molecules, and it might be better to envision a microchip that utilizes a single cell as an experimentation platform. A novel, so-called laboratory-in-a-cell concept has been described, where advantage is taken of micro- and nanotechnological tools to enable precise control of the biochemical cellular environment; these tools also offer the possibility to analyse the composition of single cells. Methods for single-cell handling and analysis are being developed and will be required for this concept to progress further.
    Original languageUndefined
    Pages (from-to)1-6
    Number of pages6
    JournalCurrent opinion in biotechnology
    Volume15
    Issue number1
    DOIs
    Publication statusPublished - 2004

    Keywords

    • IR-47829
    • METIS-218743

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