Microtiter plate-sized standalone chip holder for microenvironmental physiological control in gas-impermeable microfluidic devices

Björn Harink; Severine le Gac; David Baiao Barata; Clemens van Blitterswijk; Pamela Habibovic

doi:10.1039/C4LC00190G

Microtiter plate-sized standalone chip holder for microenvironmental physiological control in gas-impermeable microfluidic devices

Björn Harink, Severine le Gac, David Baiao Barata, Clemens van Blitterswijk, Pamela Habibovic

Faculty of Science and Technology

Research output: Contribution to journal › Article › Academic › peer-review

17 Citations (Scopus)

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Abstract

We present a microtiter plate-sized standalone chip holder for precise control of physiological conditions inside closed microfluidic cell culture systems, made from gas-impermeable materials. Specifically, we demonstrate the suitability of the holder to support cell growth in a glass chip, to allow time-lapse imaging of live cells and the creation of a hypoxic environment, all relevant for applications in regenerative medicine research.

Original language	English
Pages (from-to)	1816-1820
Number of pages	5
Journal	Lab on a chip
Volume	14
Issue number	11
DOIs	https://doi.org/10.1039/C4LC00190G
Publication status	Published - 2014

Keywords

METIS-303391
EWI-24882
IR-90527

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10.1039/C4LC00190G

http://eprints.eemcs.utwente.nl/secure2/24882/01/c4lc00190g.pdf

Cite this

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title = "Microtiter plate-sized standalone chip holder for microenvironmental physiological control in gas-impermeable microfluidic devices",

abstract = "We present a microtiter plate-sized standalone chip holder for precise control of physiological conditions inside closed microfluidic cell culture systems, made from gas-impermeable materials. Specifically, we demonstrate the suitability of the holder to support cell growth in a glass chip, to allow time-lapse imaging of live cells and the creation of a hypoxic environment, all relevant for applications in regenerative medicine research.",

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AU - Harink, Björn

AU - le Gac, Severine

AU - Baiao Barata, David

AU - van Blitterswijk, Clemens

AU - Habibovic, Pamela

PY - 2014

Y1 - 2014

N2 - We present a microtiter plate-sized standalone chip holder for precise control of physiological conditions inside closed microfluidic cell culture systems, made from gas-impermeable materials. Specifically, we demonstrate the suitability of the holder to support cell growth in a glass chip, to allow time-lapse imaging of live cells and the creation of a hypoxic environment, all relevant for applications in regenerative medicine research.

AB - We present a microtiter plate-sized standalone chip holder for precise control of physiological conditions inside closed microfluidic cell culture systems, made from gas-impermeable materials. Specifically, we demonstrate the suitability of the holder to support cell growth in a glass chip, to allow time-lapse imaging of live cells and the creation of a hypoxic environment, all relevant for applications in regenerative medicine research.

KW - METIS-303391

KW - EWI-24882

KW - IR-90527

U2 - 10.1039/C4LC00190G

DO - 10.1039/C4LC00190G

M3 - Article

SN - 1473-0197

VL - 14

SP - 1816

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JO - Lab on a chip

JF - Lab on a chip

IS - 11

ER -

Microtiter plate-sized standalone chip holder for microenvironmental physiological control in gas-impermeable microfluidic devices

Abstract

Keywords

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