Model-based stimulation optimization for chronic pain suppression using percutaneous and surgical leads in spinal cord stimulation (SCS)

V. Sankarasubramanian

    Research output: ThesisPhD Thesis - Research UT, graduation UT

    142 Downloads (Pure)

    Abstract

    The primary indication of SCS is chronic pain, in particular neuropathic pain. It is a highly debilitating condition, and in particular, is estimated to affect about one-fifth of the population in Europe (18% in the Netherlands). SCS, which uses electrical stimulation, is a valuable treatment for chronic intractable intensity and substituting it with a tingling paresthesia sensation . The overall success rate of this treatment modality is about 70%. As a potential improvement, this thesis presents the clinical and technical aspects of stimulation optimization techniques for chronic pain relief in SCS. The optimization techniques are aimed to focus primarily on improving SCS equipment. In particular, the thesis investigates the performance of novel percutaneous and surgical triple-lead configuration designs, with both longitudinal and transverse tripolar contact combinations, in a current-controlled stimulation approach. Effects of percutaneous lead alignment/misalignement, varied transversal lead spacing, preferred choice of leads (surgical/percutaneous), and IPG design are also modelled as ways to potentially improve SCS equipment.
    Original languageEnglish
    Awarding Institution
    • University of Twente
    Supervisors/Advisors
    • Buitenweg, Jan R., Advisor
    • Veltink, Petrus H., Supervisor
    • Buitenweg, Jan, Advisor
    Thesis sponsors
    Award date30 Jan 2013
    Place of PublicationEnschede
    Publisher
    Print ISBNs978-94-6191-611-2
    DOIs
    Publication statusPublished - 30 Jan 2013

    Keywords

    • IR-86740
    • Chronic pain
    • METIS-297000
    • percutaneous and surgical leads
    • EWI-23448
    • BSS-Electrical Neurostimulation
    • Spinal cord stimulation

    Fingerprint Dive into the research topics of 'Model-based stimulation optimization for chronic pain suppression using percutaneous and surgical leads in spinal cord stimulation (SCS)'. Together they form a unique fingerprint.

  • Cite this