TY - JOUR
T1 - Model studies toward trivalent cation binding by appropriately functionalized calix[4]arenes
AU - Grote gansey, M.H.B.
AU - Grote Gansey, Marcel H.B.
AU - Verboom, Willem
AU - van Veggel, F.C.J.M.
AU - Vetrogon, Victor
AU - Arnaud-Neu, Françoise
AU - Schwing-Weill, Marie-José
AU - Reinhoudt, David
PY - 1998
Y1 - 1998
N2 - Molecular modeling and molecular dynamics of a series of calix[4]arene tetracarboxylic acids and tricarboxylic acid monoamides revealed that in an aqueous environment the phenolic oxygen atoms do not participate in the complexation of Ac3+. This observation led to the design and synthesis of new calix[4]arene based ionophores, containing multiple glycine units, having an increased number of potential donor sites. Potentiometric titrations in methanol with La3+ as a non-radioactive model for Ac3+ indicated that, although the level of complexation is high for all ligands, a new calix[4]arene derivative 5 is superior at pH < 4.
AB - Molecular modeling and molecular dynamics of a series of calix[4]arene tetracarboxylic acids and tricarboxylic acid monoamides revealed that in an aqueous environment the phenolic oxygen atoms do not participate in the complexation of Ac3+. This observation led to the design and synthesis of new calix[4]arene based ionophores, containing multiple glycine units, having an increased number of potential donor sites. Potentiometric titrations in methanol with La3+ as a non-radioactive model for Ac3+ indicated that, although the level of complexation is high for all ligands, a new calix[4]arene derivative 5 is superior at pH < 4.
KW - METIS-105976
KW - IR-11064
U2 - 10.1039/a805950k
DO - 10.1039/a805950k
M3 - Article
SN - 0300-9580
VL - 1998
SP - 2351
EP - 2360
JO - Journal of the Chemical Society. Perkin transactions II
JF - Journal of the Chemical Society. Perkin transactions II
IS - 11
ER -