Modelling selective activation of small myelinated nerve fibres using a monopolar point electrode

N.J.M. Rijkhoff, N.J.M. Rijkhoff, J. Holsheimer, F.M.J. Debruyne, H. Wijkstra

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    Abstract

    The aim of this study is to investigate theoretically the possibility for activation of small myelinated nerve fibres without activating larger ones when stimulating a nerve fibre bundle using a monopolar point electrode. Therefore, the sensitivity of excitation and blocking threshold currents of nerve fibres to fibre diameter, electrode-fibre distance and pulse duration has been simulated by a computer model. A simple infinite, homogeneous volume conductor and a cathodal point source were used in combination with a model representing the electrical properties of a myelinated nerve fibre. The results show that selective activation of small myelinated fibres may be possible in a region at some distance from the electrode.
    Original languageEnglish
    Pages (from-to)762-768
    JournalMedical & biological engineering & computing
    Volume33
    Issue number6
    DOIs
    Publication statusPublished - 1995

    Keywords

    • METIS-112264
    • IR-85797
    • Modelling
    • Electrical nerve stimulation
    • Selective small fibre activation

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