Modelling selective activation of small myelinated nerve fibres using a monopolar point electrode

N.J.M. Rijkhoff; N.J.M. Rijkhoff; J. Holsheimer; F.M.J. Debruyne; H. Wijkstra

doi:10.1007/BF02523007

Modelling selective activation of small myelinated nerve fibres using a monopolar point electrode

N.J.M. Rijkhoff, N.J.M. Rijkhoff, J. Holsheimer, F.M.J. Debruyne, H. Wijkstra

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Abstract

The aim of this study is to investigate theoretically the possibility for activation of small myelinated nerve fibres without activating larger ones when stimulating a nerve fibre bundle using a monopolar point electrode. Therefore, the sensitivity of excitation and blocking threshold currents of nerve fibres to fibre diameter, electrode-fibre distance and pulse duration has been simulated by a computer model. A simple infinite, homogeneous volume conductor and a cathodal point source were used in combination with a model representing the electrical properties of a myelinated nerve fibre. The results show that selective activation of small myelinated fibres may be possible in a region at some distance from the electrode.

Original language	English
Pages (from-to)	762-768
Journal	Medical & biological engineering & computing
Volume	33
Issue number	6
DOIs	https://doi.org/10.1007/BF02523007
Publication status	Published - 1995

Keywords

METIS-112264
IR-85797
Modelling
Electrical nerve stimulation
Selective small fibre activation

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title = "Modelling selective activation of small myelinated nerve fibres using a monopolar point electrode",

abstract = "The aim of this study is to investigate theoretically the possibility for activation of small myelinated nerve fibres without activating larger ones when stimulating a nerve fibre bundle using a monopolar point electrode. Therefore, the sensitivity of excitation and blocking threshold currents of nerve fibres to fibre diameter, electrode-fibre distance and pulse duration has been simulated by a computer model. A simple infinite, homogeneous volume conductor and a cathodal point source were used in combination with a model representing the electrical properties of a myelinated nerve fibre. The results show that selective activation of small myelinated fibres may be possible in a region at some distance from the electrode.",

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AU - Rijkhoff, N.J.M.

AU - Holsheimer, J.

AU - Debruyne, F.M.J.

AU - Wijkstra, H.

PY - 1995

Y1 - 1995

N2 - The aim of this study is to investigate theoretically the possibility for activation of small myelinated nerve fibres without activating larger ones when stimulating a nerve fibre bundle using a monopolar point electrode. Therefore, the sensitivity of excitation and blocking threshold currents of nerve fibres to fibre diameter, electrode-fibre distance and pulse duration has been simulated by a computer model. A simple infinite, homogeneous volume conductor and a cathodal point source were used in combination with a model representing the electrical properties of a myelinated nerve fibre. The results show that selective activation of small myelinated fibres may be possible in a region at some distance from the electrode.

AB - The aim of this study is to investigate theoretically the possibility for activation of small myelinated nerve fibres without activating larger ones when stimulating a nerve fibre bundle using a monopolar point electrode. Therefore, the sensitivity of excitation and blocking threshold currents of nerve fibres to fibre diameter, electrode-fibre distance and pulse duration has been simulated by a computer model. A simple infinite, homogeneous volume conductor and a cathodal point source were used in combination with a model representing the electrical properties of a myelinated nerve fibre. The results show that selective activation of small myelinated fibres may be possible in a region at some distance from the electrode.

KW - METIS-112264

KW - IR-85797

KW - Modelling

KW - Electrical nerve stimulation

KW - Selective small fibre activation

U2 - 10.1007/BF02523007

DO - 10.1007/BF02523007

M3 - Article

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SN - 0140-0118

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