Modular ATR FT-IR microreactor chip for optimizing reaction conditions

Research output: Contribution to conferencePosterAcademic

8 Downloads (Pure)

Abstract

A silicon chip for attenuated total reflection (ATR) Fourier transform infrared (FT-IR) spectroscopy in combination with a modular PDMS herringbone mixer and a microreactor has been successfully fabricated and tested. The modular design allows the chip to be used for a variety of reactions. A model synthesis of 1-butyl-2,5-dimethyl-1H-pyrrole from hexane-2,5-dione with 1-butylamine has been performed on chip. When plotting the natural logarithm of the peak area corresponding to the ketone stretch vibration at 1710cm-1, against the residence time, a linear curve can be fitted, suggesting this step to be a first order reaction.
Original languageEnglish
Number of pages1
Publication statusPublished - 11 Nov 2018
Event22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018 - Kaohsiung Exhibition Center, Kaohsiung, Taiwan, Province of China
Duration: 10 Nov 201815 Nov 2018
Conference number: 22
https://cbmsociety.org/conferences/microtas2018/

Conference

Conference22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018
Abbreviated titleMicroTAS 2018
CountryTaiwan, Province of China
CityKaohsiung
Period10/11/1815/11/18
Internet address

Fingerprint

Hexanes
Silicon
Ketones
Fourier transforms
Infrared radiation
n-butylamine
2,5-dimethylpyrrole

Keywords

  • Infrared spectroscopy, attenuated total reflection, online reaction monitoring

Cite this

Lozeman, J. J. A., Vollenbroek, J. C., Bomer, J. G., de Boer, H. L., van den Berg, A., & Odijk, M. (2018). Modular ATR FT-IR microreactor chip for optimizing reaction conditions. Poster session presented at 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018, Kaohsiung, Taiwan, Province of China.
Lozeman, Jasper J.A. ; Vollenbroek, Jeroen C. ; Bomer, Johan G. ; de Boer, Hans L. ; van den Berg, Albert ; Odijk, Mathieu . / Modular ATR FT-IR microreactor chip for optimizing reaction conditions. Poster session presented at 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018, Kaohsiung, Taiwan, Province of China.1 p.
@conference{d64a8076c18b48e99a0ed3bb72e32c7a,
title = "Modular ATR FT-IR microreactor chip for optimizing reaction conditions",
abstract = "A silicon chip for attenuated total reflection (ATR) Fourier transform infrared (FT-IR) spectroscopy in combination with a modular PDMS herringbone mixer and a microreactor has been successfully fabricated and tested. The modular design allows the chip to be used for a variety of reactions. A model synthesis of 1-butyl-2,5-dimethyl-1H-pyrrole from hexane-2,5-dione with 1-butylamine has been performed on chip. When plotting the natural logarithm of the peak area corresponding to the ketone stretch vibration at 1710cm-1, against the residence time, a linear curve can be fitted, suggesting this step to be a first order reaction.",
keywords = "Infrared spectroscopy, attenuated total reflection, online reaction monitoring",
author = "Lozeman, {Jasper J.A.} and Vollenbroek, {Jeroen C.} and Bomer, {Johan G.} and {de Boer}, {Hans L.} and {van den Berg}, Albert and Mathieu Odijk",
year = "2018",
month = "11",
day = "11",
language = "English",
note = "22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018, MicroTAS 2018 ; Conference date: 10-11-2018 Through 15-11-2018",
url = "https://cbmsociety.org/conferences/microtas2018/",

}

Lozeman, JJA, Vollenbroek, JC, Bomer, JG, de Boer, HL, van den Berg, A & Odijk, M 2018, 'Modular ATR FT-IR microreactor chip for optimizing reaction conditions' 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018, Kaohsiung, Taiwan, Province of China, 10/11/18 - 15/11/18, .

Modular ATR FT-IR microreactor chip for optimizing reaction conditions. / Lozeman, Jasper J.A.; Vollenbroek, Jeroen C.; Bomer, Johan G.; de Boer, Hans L.; van den Berg, Albert ; Odijk, Mathieu .

2018. Poster session presented at 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018, Kaohsiung, Taiwan, Province of China.

Research output: Contribution to conferencePosterAcademic

TY - CONF

T1 - Modular ATR FT-IR microreactor chip for optimizing reaction conditions

AU - Lozeman, Jasper J.A.

AU - Vollenbroek, Jeroen C.

AU - Bomer, Johan G.

AU - de Boer, Hans L.

AU - van den Berg, Albert

AU - Odijk, Mathieu

PY - 2018/11/11

Y1 - 2018/11/11

N2 - A silicon chip for attenuated total reflection (ATR) Fourier transform infrared (FT-IR) spectroscopy in combination with a modular PDMS herringbone mixer and a microreactor has been successfully fabricated and tested. The modular design allows the chip to be used for a variety of reactions. A model synthesis of 1-butyl-2,5-dimethyl-1H-pyrrole from hexane-2,5-dione with 1-butylamine has been performed on chip. When plotting the natural logarithm of the peak area corresponding to the ketone stretch vibration at 1710cm-1, against the residence time, a linear curve can be fitted, suggesting this step to be a first order reaction.

AB - A silicon chip for attenuated total reflection (ATR) Fourier transform infrared (FT-IR) spectroscopy in combination with a modular PDMS herringbone mixer and a microreactor has been successfully fabricated and tested. The modular design allows the chip to be used for a variety of reactions. A model synthesis of 1-butyl-2,5-dimethyl-1H-pyrrole from hexane-2,5-dione with 1-butylamine has been performed on chip. When plotting the natural logarithm of the peak area corresponding to the ketone stretch vibration at 1710cm-1, against the residence time, a linear curve can be fitted, suggesting this step to be a first order reaction.

KW - Infrared spectroscopy, attenuated total reflection, online reaction monitoring

M3 - Poster

ER -

Lozeman JJA, Vollenbroek JC, Bomer JG, de Boer HL, van den Berg A, Odijk M. Modular ATR FT-IR microreactor chip for optimizing reaction conditions. 2018. Poster session presented at 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018, Kaohsiung, Taiwan, Province of China.