Modular ATR FT-IR microreactor chip for optimizing reaction conditions

    Research output: Contribution to conferencePoster

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    Abstract

    A silicon chip for attenuated total reflection (ATR) Fourier transform infrared (FT-IR) spectroscopy in combination with a modular PDMS herringbone mixer and a microreactor has been successfully fabricated and tested. The modular design allows the chip to be used for a variety of reactions. A model synthesis of 1-butyl-2,5-dimethyl-1H-pyrrole from hexane-2,5-dione with 1-butylamine has been performed on chip. When plotting the natural logarithm of the peak area corresponding to the ketone stretch vibration at 1710cm-1, against the residence time, a linear curve can be fitted, suggesting this step to be a first order reaction.
    Original languageEnglish
    Number of pages1
    Publication statusPublished - 11 Nov 2018
    Event22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018 - Kaohsiung Exhibition Center, Kaohsiung, Taiwan, Province of China
    Duration: 10 Nov 201815 Nov 2018
    Conference number: 22
    https://cbmsociety.org/conferences/microtas2018/

    Conference

    Conference22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018
    Abbreviated titleMicroTAS 2018
    CountryTaiwan, Province of China
    CityKaohsiung
    Period10/11/1815/11/18
    Internet address

    Keywords

    • Infrared spectroscopy, attenuated total reflection, online reaction monitoring

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  • Cite this

    Lozeman, J. J. A., Vollenbroek, J. C., Bomer, J. G., de Boer, H. L., van den Berg, A., & Odijk, M. (2018). Modular ATR FT-IR microreactor chip for optimizing reaction conditions. Poster session presented at 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018, Kaohsiung, Taiwan, Province of China.