Abstract
A silicon chip for attenuated total reflection (ATR) Fourier transform infrared (FT-IR) spectroscopy in combination with a modular PDMS herringbone mixer and a microreactor has been successfully fabricated and tested. The modular design allows the chip to be used for a variety of reactions. A model synthesis of 1-butyl-2,5-dimethyl-1H-pyrrole from hexane-2,5-dione with 1-butylamine has been performed on chip. When plotting the natural logarithm of the peak area corresponding to the ketone stretch vibration at 1710cm-1, against the residence time, a linear curve can be fitted, suggesting this step to be a first order reaction.
Original language | English |
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Number of pages | 1 |
Publication status | Published - 11 Nov 2018 |
Event | 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018 - Kaohsiung Exhibition Center, Kaohsiung, Taiwan Duration: 10 Nov 2018 → 15 Nov 2018 Conference number: 22 https://cbmsociety.org/conferences/microtas2018/ |
Conference
Conference | 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018 |
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Abbreviated title | MicroTAS 2018 |
Country/Territory | Taiwan |
City | Kaohsiung |
Period | 10/11/18 → 15/11/18 |
Internet address |
Keywords
- Infrared spectroscopy, attenuated total reflection, online reaction monitoring