Abstract
A silicon chip for attenuated total reflection (ATR) Fourier transform infrared (FT-IR) spectroscopy in combination with a modular PDMS herringbone mixer and a microreactor has been successfully fabricated and tested. The modular design allows the chip to be used for a variety of reactions. A model synthesis of 1-butyl-2,5-dimethyl-1H-pyrrole from hexane-2,5-dione with 1-butylamine has been performed on chip. When plotting the natural logarithm of the peak area corresponding to the ketone stretch vibration at 1710cm-1, against the residence time, a linear curve can be fitted, suggesting this step to be a first order reaction.
| Original language | English |
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| Title of host publication | MicroTAS 2018 |
| Subtitle of host publication | 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences |
| Editors | Fan-Gang Tseng, Gwo-Bin Lee |
| Publisher | The Chemical and Biological Microsystems Society |
| Pages | 2117-2120 |
| Number of pages | 4 |
| ISBN (Electronic) | 978-1-510-89757-1 |
| ISBN (Print) | 978-0-578-40530-8 |
| Publication status | Published - 11 Nov 2018 |
| Event | 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018 - Kaohsiung Exhibition Center, Kaohsiung, Taiwan Duration: 10 Nov 2018 → 15 Nov 2018 Conference number: 22 https://cbmsociety.org/conferences/microtas2018/ |
Conference
| Conference | 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2018 |
|---|---|
| Abbreviated title | MicroTAS 2018 |
| Country/Territory | Taiwan |
| City | Kaohsiung |
| Period | 10/11/18 → 15/11/18 |
| Internet address |
Keywords
- 2019 OA procedure
- Attenuated total reflection
- Online reaction monitoring
- Infrared spectroscopy