Modular Single-Chain Polymer Nanoparticles in Drug Delivery

Anna Pia Pauline Kröger

Research output: ThesisPhD Thesis - Research UT, graduation UT

Abstract

In this thesis, thiol-Michael addition was employed in the intramolecular crosslinking of thiol polymers to yield a variety of single-chain polymer nanoparticles (SCNPs). These polymer nanoparticles are ~10 nm in diameter, which is markedly smaller than conventional polymer nanoparticles. Furthermore, altered biodistribution behavior is anticipated, with improved targeting characteristics towards certain areas in the human body.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • University of Twente
Supervisors/Advisors
  • Grijpma, D.W., Supervisor
  • Cornelissen, Jeroen, Supervisor
  • Paulusse, J.M.J., Co-Supervisor
Award date3 Oct 2018
Place of PublicationEnschede
Publisher
Print ISBNs978-90-365-4623-2
DOIs
Publication statusPublished - 3 Oct 2018

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