TY - JOUR
T1 - Mold-based application of laser-induced periodic surface structures (LIPPS) on biomaterials for nanoscale patterning
AU - Hendrikson, W.J.
AU - Masman-Bakker, W.
AU - van Bochove, Bas
AU - Skolski, J.Z.P.
AU - Eichstädt, J.
AU - Koopman, Hubertus F.J.M.
AU - van Blitterswijk, Clemens
AU - Grijpma, Dirk W.
AU - Römer, Gerardus Richardus, Bernardus, Engelina
AU - Moroni, Lorenzo
AU - Rouwkema, Jeroen
PY - 2016/9/3
Y1 - 2016/9/3
N2 - Laser-induced periodic surface structures (LIPSS) are highly regular, but at the same time contain a certain level of disorder. The application of LIPSS is a promising method to functionalize biomaterials. However, the absorption of laser energy of most polymer biomaterials is insufficient for the direct application of LIPSS. Here, we report the application of LIPSS to relevant biomaterials using a two-step approach. First, LIPSS are fabricated on a stainless steel surface. Then, the structures are replicated onto biomaterials using the steel as a mold. Results show that LIPSS can be transferred successfully using this approach, and that human mesenchymal stromal cells respond to the transferred structures. With this approach, the range of biomaterials that can be supplied with LIPSS increases dramatically.
AB - Laser-induced periodic surface structures (LIPSS) are highly regular, but at the same time contain a certain level of disorder. The application of LIPSS is a promising method to functionalize biomaterials. However, the absorption of laser energy of most polymer biomaterials is insufficient for the direct application of LIPSS. Here, we report the application of LIPSS to relevant biomaterials using a two-step approach. First, LIPSS are fabricated on a stainless steel surface. Then, the structures are replicated onto biomaterials using the steel as a mold. Results show that LIPSS can be transferred successfully using this approach, and that human mesenchymal stromal cells respond to the transferred structures. With this approach, the range of biomaterials that can be supplied with LIPSS increases dramatically.
U2 - 10.1002/mabi.201500270
DO - 10.1002/mabi.201500270
M3 - Article
VL - 16
SP - 43
EP - 49
JO - Macromolecular bioscience
JF - Macromolecular bioscience
SN - 1616-5187
IS - 1
ER -