Abstract
Be specific: A supramolecular adsorbate consisting of an adamantyl group (red) and an oligo(ethylene glycol) chain has been designed to prevent nonspecific protein adsorption at cyclodextrin molecular printboards. The adamantyl group allows specific and reversible interactions. Specific immobilization of proteins (gray) is possible through multivalent orthogonal linkers by effective replacement of the monovalent adsorbate (Ni2+ ions (green) may be needed; see picture).
| Original language | English |
|---|---|
| Pages (from-to) | 4104-4107 |
| Number of pages | 4 |
| Journal | Angewandte Chemie, International Edition in English |
| Volume | 46 |
| Issue number | 22 |
| DOIs | |
| Publication status | Published - 2007 |
Keywords
- 2020 OA procedure
- Cyclodextrins
- Host-guest systems
- Proteins
- Noncovalent interactions
- Self-assembled monolayers
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