Molecular printboards as general platforms for protein immobilization

This thesis describes the selective attachment of proteins to β-cyclodextrin (βCD) self-assembled monolayers (SAMs), termed molecular printboards through multivalent orthogonal interactions. It is shown that the molecular printboards allow different assembly pathways for the build-up of (complex) bionanostructures. In the assembly of these bionanostructures, control over stability, stoichiometry of binding, and orientation is achieved. A monovalent supramolecular blocking agent can be applied to prevent nonspecific immobilization of proteins to the molecular printboard, while the specific attachment of proteins via multivalent interactions is still possible.