Monitoring Cerebral perfusion using near infrared spectroscopy and laser doppler flowmetry

J.H.G.M. Klaessens, R.G.M. Kolkman, J.C.W. Hopman, Erwin Hondebrink, K.D. Liem, Wiendelt Steenbergen, F.F.M. de Mul, J.M. Thijssen

Research output: Contribution to journalArticleAcademicpeer-review

17 Citations (Scopus)

Abstract

This paper describes the simultaneous use of two, noninvasive, near-infrared techniques near-infrared spectroscopy (NIRS) and a continuous wave NIR laser Doppler flow system (LDF) to measure changes in the blood oxygenation, blood concentration and blood flow velocity in the brain. A piglet was used as animal model. A controlled change in the arterial CO2 pressure (PaCO2) was applied for achieving changes in the listed cerebrovascular parameters. The time courses of blood concentration parameters (NIRS) and RMS blood flow velocity (LDF) were found to correspond closely with those of carotid blood flow and arterial carbon dioxide pressure (PaCO2). This result shows the additional value of LDF when combined with NIRS, preferably in one instrument. Development of pulsed LDF for regional blood flow measurement is indicated.
Original languageUndefined
Pages (from-to)N35-N40
Number of pages6
JournalPhysiological measurement
Volume24
DOIs
Publication statusPublished - 2003

Keywords

  • IR-40564
  • METIS-212525

Cite this

Klaessens, J. H. G. M., Kolkman, R. G. M., Hopman, J. C. W., Hondebrink, E., Liem, K. D., Steenbergen, W., ... Thijssen, J. M. (2003). Monitoring Cerebral perfusion using near infrared spectroscopy and laser doppler flowmetry. Physiological measurement, 24, N35-N40. https://doi.org/10.1088/0967-3334/24/4/N03
Klaessens, J.H.G.M. ; Kolkman, R.G.M. ; Hopman, J.C.W. ; Hondebrink, Erwin ; Liem, K.D. ; Steenbergen, Wiendelt ; de Mul, F.F.M. ; Thijssen, J.M. / Monitoring Cerebral perfusion using near infrared spectroscopy and laser doppler flowmetry. In: Physiological measurement. 2003 ; Vol. 24. pp. N35-N40.
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abstract = "This paper describes the simultaneous use of two, noninvasive, near-infrared techniques near-infrared spectroscopy (NIRS) and a continuous wave NIR laser Doppler flow system (LDF) to measure changes in the blood oxygenation, blood concentration and blood flow velocity in the brain. A piglet was used as animal model. A controlled change in the arterial CO2 pressure (PaCO2) was applied for achieving changes in the listed cerebrovascular parameters. The time courses of blood concentration parameters (NIRS) and RMS blood flow velocity (LDF) were found to correspond closely with those of carotid blood flow and arterial carbon dioxide pressure (PaCO2). This result shows the additional value of LDF when combined with NIRS, preferably in one instrument. Development of pulsed LDF for regional blood flow measurement is indicated.",
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author = "J.H.G.M. Klaessens and R.G.M. Kolkman and J.C.W. Hopman and Erwin Hondebrink and K.D. Liem and Wiendelt Steenbergen and {de Mul}, F.F.M. and J.M. Thijssen",
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volume = "24",
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journal = "Physiological measurement",
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Klaessens, JHGM, Kolkman, RGM, Hopman, JCW, Hondebrink, E, Liem, KD, Steenbergen, W, de Mul, FFM & Thijssen, JM 2003, 'Monitoring Cerebral perfusion using near infrared spectroscopy and laser doppler flowmetry', Physiological measurement, vol. 24, pp. N35-N40. https://doi.org/10.1088/0967-3334/24/4/N03

Monitoring Cerebral perfusion using near infrared spectroscopy and laser doppler flowmetry. / Klaessens, J.H.G.M.; Kolkman, R.G.M.; Hopman, J.C.W.; Hondebrink, Erwin; Liem, K.D.; Steenbergen, Wiendelt; de Mul, F.F.M.; Thijssen, J.M.

In: Physiological measurement, Vol. 24, 2003, p. N35-N40.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Monitoring Cerebral perfusion using near infrared spectroscopy and laser doppler flowmetry

AU - Klaessens, J.H.G.M.

AU - Kolkman, R.G.M.

AU - Hopman, J.C.W.

AU - Hondebrink, Erwin

AU - Liem, K.D.

AU - Steenbergen, Wiendelt

AU - de Mul, F.F.M.

AU - Thijssen, J.M.

PY - 2003

Y1 - 2003

N2 - This paper describes the simultaneous use of two, noninvasive, near-infrared techniques near-infrared spectroscopy (NIRS) and a continuous wave NIR laser Doppler flow system (LDF) to measure changes in the blood oxygenation, blood concentration and blood flow velocity in the brain. A piglet was used as animal model. A controlled change in the arterial CO2 pressure (PaCO2) was applied for achieving changes in the listed cerebrovascular parameters. The time courses of blood concentration parameters (NIRS) and RMS blood flow velocity (LDF) were found to correspond closely with those of carotid blood flow and arterial carbon dioxide pressure (PaCO2). This result shows the additional value of LDF when combined with NIRS, preferably in one instrument. Development of pulsed LDF for regional blood flow measurement is indicated.

AB - This paper describes the simultaneous use of two, noninvasive, near-infrared techniques near-infrared spectroscopy (NIRS) and a continuous wave NIR laser Doppler flow system (LDF) to measure changes in the blood oxygenation, blood concentration and blood flow velocity in the brain. A piglet was used as animal model. A controlled change in the arterial CO2 pressure (PaCO2) was applied for achieving changes in the listed cerebrovascular parameters. The time courses of blood concentration parameters (NIRS) and RMS blood flow velocity (LDF) were found to correspond closely with those of carotid blood flow and arterial carbon dioxide pressure (PaCO2). This result shows the additional value of LDF when combined with NIRS, preferably in one instrument. Development of pulsed LDF for regional blood flow measurement is indicated.

KW - IR-40564

KW - METIS-212525

U2 - 10.1088/0967-3334/24/4/N03

DO - 10.1088/0967-3334/24/4/N03

M3 - Article

VL - 24

SP - N35-N40

JO - Physiological measurement

JF - Physiological measurement

SN - 0967-3334

ER -