Monodisperse Attoliter Droplet Formation Using a Nano-Microchannel Interface

We demonstrate the production of sub-micrometer diameter monodisperse droplets by using a nano-micro channel interface. A perfectly steady nanoscopic liquid filament can be formed by a geometric confinement which eventually gives rise to a stable production of nearly perfectly monodisperse droplets. In a certain range of physical parameters and geometrical configurations, the liquid filament size and therefore the droplet size is determined by the nanochannel geometry, mainly its height which determines the Laplace pressure. Droplet diameters of 0.7~3.5 �?�m (aL~fL volume) have been produced using different size nanochannels.