Multi-axial loading micromechanics of the cement-bone interface in postmortem retrievals and lab-prepared specimens

Mark A. Miller, Amos Race, Daan Waanders, Richard Cleary, Dennis Janssen, Nico Verdonschot, Kenneth A. Mann

    Research output: Contribution to journalArticleAcademicpeer-review


    Maintaining adequate fixation between cement and bone is important for successful long term survival of cemented total joint replacements. Mixed-mode loading conditions (combination of tension/compression and shear) are present during in vivo loading, but the micromotion response of the interface to these conditions is not fully understood.

    Non-destructive, multi-axial loading experiments were conducted on laboratory prepared (n=6) and postmortem (n=6) human cement–bone interfaces. Specimens were mounted in custom loading discs and loaded at 0°, 30°, 60°, and 90° relative to the interface plane where 0° represents normal loading to the interface, and 90° represents shear loading along the longitudinal axis of the femur. Axial compliance did not depend on loading angle for laboratory prepared (p=0.96) or postmortem specimens (p=0.62). The cement–bone interface was more compliant under tensile than compressive loading at the 0° loading angle only (p=0.024). The coupled transverse to axial compliance ratio, which is a measure of the coupled motion, was small for laboratory prepared (0.115 ± 0.115) and postmortem specimens (0.142 ± 0.101). There was a moderately strong inverse relationship between interface compliance and contact index (r2=0.65).

    From a computational modeling perspective, the results of the current study support the concept that the cement–bone interface could be numerically implemented as a compliant layer with the same initial stiffness in tension and shear directions. The magnitude of the compliance could be modified to simulate immediate post-operative conditions (using laboratory prepared data set) or long-term remodeling (using postmortem data set).
    Original languageEnglish
    Pages (from-to)366-374
    Number of pages9
    JournalJournal of the mechanical behavior of biomedical materials
    Issue number3
    Publication statusPublished - 2011


    • METIS-283558
    • Interface
    • Micro-mechanics
    • Joint replacement
    • Micro-motion
    • Postmortem
    • Cement
    • Bone
    • Loosening


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