Abstract
Extracellular vesicles have emerged in recent years as highly promising for understanding cell communication, drug delivery, and medical applications. Specifically, tumor-derived extracellular vesicles (tdEVs) have demonstrated excellent prognostic value in cancer diagnostics compared to imaging approaches. Despite the growing body of expertise regarding EVs, great challenges remain, notably in their handling and characterization. In complex media, other particles with similar characteristics may occlude measurements. Here, a platform is presented for the immunocapturing of tdEVs for identifying their origin followed by further multi-modal analysis by Raman spectroscopy, confocal microscopy and atomic force microscopy (AFM).
Original language | English |
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Title of host publication | MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
Publisher | The Chemical and Biological Microsystems Society |
Pages | 404-405 |
Number of pages | 2 |
ISBN (Electronic) | 9781733419017 |
Publication status | Published - 2020 |
Event | 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2020 - Virtual Event Duration: 4 Oct 2020 → 9 Oct 2020 Conference number: 24 https://microtas2020.org/ |
Publication series
Name | MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
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Conference
Conference | 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, µTAS 2020 |
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Abbreviated title | MicroTAS 2020 |
City | Virtual Event |
Period | 4/10/20 → 9/10/20 |
Internet address |
Keywords
- Cancer diagnostics
- Extracellular vesicles
- Multi-modal analysis
- Surface modification
- TdEVs