Abstract
From experiments, it appears to be possible to stimulate a neuron by depolarisation of the lower membrane patch, the sealing part of the membrane, using a nano-ampere current through the extracellular electrode. Also, a stimulation window is observed. These findings can be explained by a finite element model of the neuron-electrode interface which permits geometry based dynamic modeling of the neuron-electrode interface and can be used to explore the requirements for lower membrane stimulation in more detail. An intracellular action potential develops if the current through the lower membrane is able to depolarize the upper membrane sufficiently.
Original language | Undefined |
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Title of host publication | Proceedings 23rd International Conference of the IEEE Engineering in Medicine and Biology Society, Istanbul, Turkey |
Place of Publication | Piscattaway, USA |
Publisher | IEEE |
Pages | - |
Number of pages | 4 |
ISBN (Print) | 0-7803-7213-1 |
DOIs | |
Publication status | Published - 25 Oct 2001 |
Event | 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2001 - Istanbul, Turkey Duration: 25 Oct 2001 → 28 Oct 2001 Conference number: 23 |
Publication series
Name | |
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Publisher | IEEE |
Volume | 1 |
Conference
Conference | 23rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2001 |
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Abbreviated title | EMBC |
Country | Turkey |
City | Istanbul |
Period | 25/10/01 → 28/10/01 |
Keywords
- IR-42181
- METIS-200705