Nanoparticle Aggregate-Based Fluorescence Enhancement for Highly Sensitive and Reproducible Detection of DNA

C. Annink, Ron Gill

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Scopus)


Sensitive detection of DNA at the sub picomolar range is demonstrated using a magnetic bead sandwich hybridization assay coupled with surface-enhanced fluorescence (SEF)-based amplification. Unlike enzymatic amplification, the SEF amplification step does not add any additional background to the measurement and does not cause a significant increase in the coefficient of variance (CV).
Original languageUndefined
Pages (from-to)943-947
Number of pages5
JournalParticle & particle systems characterization
Issue number9
Publication statusPublished - 2014


  • METIS-306143
  • IR-94933

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