Nanoreactors via encapsulation of catalytic gold nanoparticles within cowpea chlorotic mottle virus protein cages

Aijie Liu, Mark V. de Ruiter, Stan J. Maassen, Jeroen J.L.M. Cornelissen*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterAcademicpeer-review

1 Citation (Scopus)

Abstract

Viral protein cage-based nanoreactors can be generated by encapsulation of catalytic metal nanoparticles within the capsid structure. In this method, coat proteins of the cowpea chlorotic mottle virus (CCMV) are used to sequester gold nanoparticles (Au NPs) in buffered solutions at neutral pH to form CCMV-Au hybrid nanoparticles. This chapter describes detailed methods for the encapsulation of Au NPs into CCMV protein cages. Protocols for the reduction of nitroarenes by using CCMV-Au NPs as catalyst are described as an example for the catalytic activity of Au NPs in the protein cages.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages1-9
Number of pages9
Volume1798
DOIs
Publication statusPublished - 1 Jan 2018

Publication series

NameMethods in Molecular Biology
Volume1798
ISSN (Print)1064-3745

Keywords

  • Catalysis
  • CCMV
  • Encapsulation
  • Gold nanoparticle
  • Nanoreactor
  • Protein cage

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