Nanostructures via noncovalent synthesis: 144 hydrogen bonds bring together 27 components

V. Paraschiv, Mercedes Crego Calama, R.H. Fokkens, Clemens J. Padberg, P. Timmerman, David Reinhoudt

Research output: Contribution to journalArticleAcademicpeer-review

34 Citations (Scopus)


This paper describes the spontaneous and reversible assembly of 20 kDa synthetic hydrogen-bonded assemblies via the formation of 144 cooperative hydrogen bonds. These nanostructures (3.0 × 5.5 nm), consisting of 27 different components, have been carefully characterized using a combination of 1H NMR spectroscopy, MALDI-TOF MS using Ag+-labeling, gel permeation chromatography, and CD spectroscopy.
Original languageUndefined
Pages (from-to)8297-8301
JournalJournal of organic chemistry
Issue number25
Publication statusPublished - 2001


  • METIS-203077
  • IR-36800

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