Near-surface effects on the controlled motion of magnetotactic bacteria

Islam S.M. Khalil, Ahmet Fatih Tabak, Tijmen Hageman, Mohamed Ewis, Marc Pichel, Mohamed E. Mitwally, Nermeen Serag El-Din, Leon Abelmann, Metin Sitti

    Research output: Chapter in Book/Report/Conference proceedingConference contributionAcademicpeer-review

    7 Citations (Scopus)

    Abstract

    Magnetotactic bacteria have the potential to controllably reach stagnant fluids inside the human body and achieve targeted drug delivery. In this application, motion of the magnetotactic bacteria is influenced by the near-surface effects such as the background flows and surface interactions. Here, we provide a hydrodynamic model of bipolarly-flagellated magnetotactic bacteria (Magnetospirillum gryphiswaldense strain MSR-1) based on the resistive-force theory to resemble the helical body and the two flagella bundles, and investigate their swimming characteristics in two environments, i.e., free-space and near flat walls. The free-space is studied using capillary tubes with depth of 200 ßm, whereas the effect of the flat walls is investigated using microfluidic chips with depth of 5 μm. We find that the linear speeds of bacteria near- and far-surface are 36±16.4 μm/s (mean±s.d.) and 46±6.8 μm/s, respectively, whereas their respective angular velocities are 12.5±5.7 rad/s and 13.5±5.0 rad/s.

    Original languageEnglish
    Title of host publicationICRA 2017 - IEEE International Conference on Robotics and Automation
    PublisherIEEE
    Pages5976-5982
    Number of pages7
    ISBN (Electronic)9781509046331
    DOIs
    Publication statusPublished - 21 Jul 2017
    Event2017 IEEE International Conference on Robotics and Automation, ICRA 2017: Innovation, Entrepreneurship, and Real-world Solutions - Singapore, Singapore
    Duration: 29 May 20173 Jun 2017
    http://www.icra2017.org/

    Conference

    Conference2017 IEEE International Conference on Robotics and Automation, ICRA 2017
    Abbreviated titleICRA 2017
    CountrySingapore
    CitySingapore
    Period29/05/173/06/17
    Internet address

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