Network bursts in cortical neuronal cultures: 'noise - versus pacemaker'- driven neural network simulations

T. Gritsun, J. Stegenga, Jakob le Feber, Wim Rutten

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    Abstract

    In this paper we address the issue of spontaneous bursting activity in cortical neuronal cultures and explain what might cause this collective behavior using computer simulations of two different neural network models. While the common approach to acivate a passive network is done by introducing synaptic noise, we show that a small subset of pacemaker neurons can trigger network bursts which better resemble experimental bursts.
    Original languageUndefined
    Title of host publicationProceedings of the 4th Int. IEEE EMBS Conf. on Neural Engineering
    Place of PublicationPiscataway
    PublisherIEEE Engineering in Medicine and Biology Society
    Pages626-628
    Number of pages3
    ISBN (Print)978-1-4244-2073-5
    DOIs
    Publication statusPublished - 29 Apr 2009
    Event4th International IEEE/EMBS Conference on Neural Engineering, NER 2009 - Antalya, Turkey
    Duration: 29 Apr 20092 May 2009
    Conference number: 4

    Publication series

    Name
    PublisherIEEE-EMBS

    Conference

    Conference4th International IEEE/EMBS Conference on Neural Engineering, NER 2009
    Abbreviated titleNER
    CountryTurkey
    CityAntalya
    Period29/04/092/05/09

    Keywords

    • network bursts cortical neuronal cultures
    • Synaptic Connectivity
    • cortical neuronal cultures
    • IR-62813
    • EWI-15368
    • Network bursts
    • METIS-265210
    • random recurrent neuronal network

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