Abstract
Adsorbed layers of polyediylenoxide-polypropylenoxide (PEO-PPO) blockcopolymers were tested as neurophobic background coatings in neuronal patterning studies over a time period of 30 days. Microprinted tracks of polyethylenimine (PEI) were used as the neuron-adhesive part of the pattern. Results showed that PEO-PPO surfactants F108 and F127 (Synperonics, ICI) significantly reduced the growth of neuronal tissue when adsorbed on Polyimide and Fluorocarbon surfaces up till 8 days. Also survival of neuronal tissue was not negatively affected by the PEO-PPO. Viability of the cultures was assessed after 30 days and showed viability factors above 0.9 (scale 0 to 1).
| Original language | English |
|---|---|
| Title of host publication | Second joint IEEE-EMBS/BMES Conference 2002 |
| Publisher | IEEE |
| Pages | 2121-2122 |
| Number of pages | 2 |
| ISBN (Print) | 0-7803-7613-7, 0-7803-7612-9 |
| DOIs | |
| Publication status | Published - 23 Oct 2002 |
| Event | Second Joint EMBS/BMES Conference 2002 - Houston, United States Duration: 23 Oct 2002 → 26 Oct 2002 Conference number: 2 |
Conference
| Conference | Second Joint EMBS/BMES Conference 2002 |
|---|---|
| Country/Territory | United States |
| City | Houston |
| Period | 23/10/02 → 26/10/02 |
Keywords
- n/a OA procedure
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