New generation of integrated probes for laser Doppler perfusion monitoring: construction and in vivo results

A. Serov; Sj. Oosterbaan; J. Nieland; H. van Kranenburg; R. Verboom; H.H.T.Ph. Bekman; F.F.M. de Mul; W. Steenbergen

doi:10.1117/12.466644

New generation of integrated probes for laser Doppler perfusion monitoring: construction and in vivo results

A. Serov
, Sj. Oosterbaan
, J. Nieland
, H. van Kranenburg
, R. Verboom
, H.H.T.Ph. Bekman
, F.F.M. de Mul
, W. Steenbergen

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

1 Citation (Scopus)

8 Downloads (Pure)

Abstract

Integrated probes have been developed containing the essential optoelectronic components necessary for monitoring tissue perfusion using the laser Doppler principle. The device contains a VCSEL for illumination, and a chip with photodetectors, amplifiers for signal enhancement, and digital circuitry for external probe control. VCSEL and detector chip are mounted on a common ceramic platform. A Peltier element may be included for temperature stabilisation, or thermal cycling for physiological purposes. Two special chips have been developed: one containing an array of five detectors, at various distances from the laser, which will allow for some degree of depth discrimination, and a single detector chip. In this paper the probe designs are presented and some results of in vivo measurements are shown.

Original language	English
Title of host publication	Biomedical Diagnostic, Guidance, and Surgical-Assist Systems IV
Editors	T. Vo-Dinh, D.A. Benaron, W.S. Grundfest
Publisher	SPIE
Pages	165-172
Number of pages	8
DOIs	https://doi.org/10.1117/12.466644
Publication status	Published - 20 Jan 2002
Event	Biomedical Diagnostic, Guidance, and Surgical-Assist Systems IV - San Jose, CA, USA Duration: 20 Jan 2002 → 21 Jan 2002

Publication series

Name	Proceedings of SPIE
Publisher	SPIE
Number	7
Volume	3
ISSN (Print)	1605-7422

Conference

Conference	Biomedical Diagnostic, Guidance, and Surgical-Assist Systems IV
Period	20/01/02 → 21/01/02
Other	20-21 January 2002

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10.1117/12.466644

Cite this

Serov, A., Oosterbaan, S., Nieland, J., van Kranenburg, H., Verboom, R., Bekman, H. H. T. P., de Mul, F. F. M., & Steenbergen, W. (2002). New generation of integrated probes for laser Doppler perfusion monitoring: construction and in vivo results. In T. Vo-Dinh, D. A. Benaron, & W. S. Grundfest (Eds.), Biomedical Diagnostic, Guidance, and Surgical-Assist Systems IV (pp. 165-172). (Proceedings of SPIE; Vol. 3, No. 7). SPIE. https://doi.org/10.1117/12.466644

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title = "New generation of integrated probes for laser Doppler perfusion monitoring: construction and in vivo results",

abstract = "Integrated probes have been developed containing the essential optoelectronic components necessary for monitoring tissue perfusion using the laser Doppler principle. The device contains a VCSEL for illumination, and a chip with photodetectors, amplifiers for signal enhancement, and digital circuitry for external probe control. VCSEL and detector chip are mounted on a common ceramic platform. A Peltier element may be included for temperature stabilisation, or thermal cycling for physiological purposes. Two special chips have been developed: one containing an array of five detectors, at various distances from the laser, which will allow for some degree of depth discrimination, and a single detector chip. In this paper the probe designs are presented and some results of in vivo measurements are shown.",

author = "A. Serov and Sj. Oosterbaan and J. Nieland and \{van Kranenburg\}, H. and R. Verboom and H.H.T.Ph. Bekman and \{de Mul\}, F.F.M. and W. Steenbergen",

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editor = "T. Vo-Dinh and D.A. Benaron and W.S. Grundfest",

booktitle = "Biomedical Diagnostic, Guidance, and Surgical-Assist Systems IV",

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note = "Biomedical Diagnostic, Guidance, and Surgical-Assist Systems IV ; Conference date: 20-01-2002 Through 21-01-2002",

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Serov, A, Oosterbaan, S, Nieland, J, van Kranenburg, H, Verboom, R, Bekman, HHTP, de Mul, FFM & Steenbergen, W 2002, New generation of integrated probes for laser Doppler perfusion monitoring: construction and in vivo results. in T Vo-Dinh, DA Benaron & WS Grundfest (eds), Biomedical Diagnostic, Guidance, and Surgical-Assist Systems IV. Proceedings of SPIE, no. 7, vol. 3, SPIE, pp. 165-172, Biomedical Diagnostic, Guidance, and Surgical-Assist Systems IV, 20/01/02. https://doi.org/10.1117/12.466644

New generation of integrated probes for laser Doppler perfusion monitoring: construction and in vivo results. / Serov, A.; Oosterbaan, Sj.; Nieland, J. et al.
Biomedical Diagnostic, Guidance, and Surgical-Assist Systems IV. ed. / T. Vo-Dinh; D.A. Benaron; W.S. Grundfest. SPIE, 2002. p. 165-172 (Proceedings of SPIE; Vol. 3, No. 7).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic › peer-review

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AU - Steenbergen, W.

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AB - Integrated probes have been developed containing the essential optoelectronic components necessary for monitoring tissue perfusion using the laser Doppler principle. The device contains a VCSEL for illumination, and a chip with photodetectors, amplifiers for signal enhancement, and digital circuitry for external probe control. VCSEL and detector chip are mounted on a common ceramic platform. A Peltier element may be included for temperature stabilisation, or thermal cycling for physiological purposes. Two special chips have been developed: one containing an array of five detectors, at various distances from the laser, which will allow for some degree of depth discrimination, and a single detector chip. In this paper the probe designs are presented and some results of in vivo measurements are shown.

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Serov A, Oosterbaan S, Nieland J, van Kranenburg H, Verboom R, Bekman HHTP et al. New generation of integrated probes for laser Doppler perfusion monitoring: construction and in vivo results. In Vo-Dinh T, Benaron DA, Grundfest WS, editors, Biomedical Diagnostic, Guidance, and Surgical-Assist Systems IV. SPIE. 2002. p. 165-172. (Proceedings of SPIE; 7). doi: 10.1117/12.466644

New generation of integrated probes for laser Doppler perfusion monitoring: construction and in vivo results

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