Nociceptive detection probability depends on the temporal properties of electrocutaneous stimuli

Robert Doll; A.C.A. Maten; S.P.G. Spaan; Petrus H. Veltink; Jan R. Buitenweg

Nociceptive detection probability depends on the temporal properties of electrocutaneous stimuli

Robert Doll, A.C.A. Maten, S.P.G. Spaan, Petrus H. Veltink, Jan R. Buitenweg

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic

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Abstract

Electrical stimulation of the skin using a needle-electrode specifically activates nociceptive nerve fibres. The detection of such stimuli by subjects depends on the activation of subsequent nociceptive mechanisms. Activation of these mechanisms depends on the temporal stimulus properties, such as the pulse-width, number of pulses, and inter-pulse interval. Here, we study whether different temporal stimulus properties do not only affect the detection threshold, but also the slope of the psychophysical curve. 30 healthy human subjects were included in a 10-minute psychophysical experiment. The results showed that the psychophysical function, and thus the detection probability, depends on stimulus properties. This suggests that additional estimation of the psychophysical curve could be useful for improved observation of (several) nociceptive mechanisms.

Original language	Undefined
Title of host publication	5th Dutch Conference on Bio-Medical Engineering
Place of Publication	Egmond aan Zee
Publisher	BME
Pages	146-146
Number of pages	1
ISBN (Print)	not assigned
Publication status	Published - Jan 2015
Event	5th Dutch Bio-Medical Engineering Conference, BME 2015 - Hotel Zuiderduin, Egmond aan Zee, Netherlands Duration: 22 Jan 2015 → 23 Jan 2015 Conference number: 5 http://www.bme2015.nl/

Publication series

Name
Publisher	BME

Conference

Conference	5th Dutch Bio-Medical Engineering Conference, BME 2015
Abbreviated title	BME 2015
Country	Netherlands
City	Egmond aan Zee
Period	22/01/15 → 23/01/15
Internet address	http://www.bme2015.nl/

Keywords

BSS-Central mechanisms underlying chronic pain
Nociception
Electrical stimulation
Pain
METIS-312489
EWI-25681
IR-94061
Psychophysics
human subjects

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Cite this

@inproceedings{33128eb1174f4741b032660ea6c3e87d,

title = "Nociceptive detection probability depends on the temporal properties of electrocutaneous stimuli",

abstract = "Electrical stimulation of the skin using a needle-electrode specifically activates nociceptive nerve fibres. The detection of such stimuli by subjects depends on the activation of subsequent nociceptive mechanisms. Activation of these mechanisms depends on the temporal stimulus properties, such as the pulse-width, number of pulses, and inter-pulse interval. Here, we study whether different temporal stimulus properties do not only affect the detection threshold, but also the slope of the psychophysical curve. 30 healthy human subjects were included in a 10-minute psychophysical experiment. The results showed that the psychophysical function, and thus the detection probability, depends on stimulus properties. This suggests that additional estimation of the psychophysical curve could be useful for improved observation of (several) nociceptive mechanisms.",

keywords = "BSS-Central mechanisms underlying chronic pain, Nociception, Electrical stimulation, Pain, METIS-312489, EWI-25681, IR-94061, Psychophysics, human subjects",

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language = "Undefined",

isbn = "not assigned",

publisher = "BME",

pages = "146--146",

booktitle = "5th Dutch Conference on Bio-Medical Engineering",

note = "null ; Conference date: 22-01-2015 Through 23-01-2015",

url = "http://www.bme2015.nl/",

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Nociceptive detection probability depends on the temporal properties of electrocutaneous stimuli. / Doll, Robert; Maten, A.C.A.; Spaan, S.P.G.; Veltink, Petrus H.; Buitenweg, Jan R.

5th Dutch Conference on Bio-Medical Engineering. Egmond aan Zee : BME, 2015. p. 146-146.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic

TY - GEN

T1 - Nociceptive detection probability depends on the temporal properties of electrocutaneous stimuli

AU - Doll, Robert

AU - Maten, A.C.A.

AU - Spaan, S.P.G.

AU - Veltink, Petrus H.

AU - Buitenweg, Jan R.

N1 - Conference code: 5

PY - 2015/1

Y1 - 2015/1

N2 - Electrical stimulation of the skin using a needle-electrode specifically activates nociceptive nerve fibres. The detection of such stimuli by subjects depends on the activation of subsequent nociceptive mechanisms. Activation of these mechanisms depends on the temporal stimulus properties, such as the pulse-width, number of pulses, and inter-pulse interval. Here, we study whether different temporal stimulus properties do not only affect the detection threshold, but also the slope of the psychophysical curve. 30 healthy human subjects were included in a 10-minute psychophysical experiment. The results showed that the psychophysical function, and thus the detection probability, depends on stimulus properties. This suggests that additional estimation of the psychophysical curve could be useful for improved observation of (several) nociceptive mechanisms.

AB - Electrical stimulation of the skin using a needle-electrode specifically activates nociceptive nerve fibres. The detection of such stimuli by subjects depends on the activation of subsequent nociceptive mechanisms. Activation of these mechanisms depends on the temporal stimulus properties, such as the pulse-width, number of pulses, and inter-pulse interval. Here, we study whether different temporal stimulus properties do not only affect the detection threshold, but also the slope of the psychophysical curve. 30 healthy human subjects were included in a 10-minute psychophysical experiment. The results showed that the psychophysical function, and thus the detection probability, depends on stimulus properties. This suggests that additional estimation of the psychophysical curve could be useful for improved observation of (several) nociceptive mechanisms.

KW - BSS-Central mechanisms underlying chronic pain

KW - Nociception

KW - Electrical stimulation

KW - Pain

KW - METIS-312489

KW - EWI-25681

KW - IR-94061

KW - Psychophysics

KW - human subjects

M3 - Conference contribution

SN - not assigned

SP - 146

EP - 146

BT - 5th Dutch Conference on Bio-Medical Engineering

PB - BME

CY - Egmond aan Zee

Y2 - 22 January 2015 through 23 January 2015

ER -