Nociceptive detection probability depends on the temporal properties of electrocutaneous stimuli

R.J. (Robert) Doll; A.C.A. (Floor) Maten; S.P.G. (Sjoerd) Spaan; P.H. (Peter) Veltink; J.R. (Jan) Buitenweg

Nociceptive detection probability depends on the temporal properties of electrocutaneous stimuli

R.J. (Robert) Doll, A.C.A. (Floor) Maten, S.P.G. (Sjoerd) Spaan, P.H. (Peter) Veltink, J.R. (Jan) Buitenweg

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic

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Abstract

Electrical stimulation of the skin using a needle-electrode specifically activates nociceptive nerve fibres. The detection of such stimuli by subjects depends on the activation of subsequent nociceptive mechanisms. Activation of these mechanisms depends on the temporal stimulus properties, such as the pulse-width, number of pulses, and inter-pulse interval. Here, we study whether different temporal stimulus properties do not only affect the detection threshold, but also the slope of the psychophysical curve. 30 healthy human subjects were included in a 10-minute psychophysical experiment. The results showed that the psychophysical function, and thus the detection probability, depends on stimulus properties. This suggests that additional estimation of the psychophysical curve could be useful for improved observation of (several) nociceptive mechanisms.

Original language	English
Title of host publication	5th Dutch Conference on Bio-Medical Engineering
Place of Publication	Egmond aan Zee, The Netherlands
Publisher	BME
Pages	146-146
Number of pages	1
Publication status	Published - 2015
Event	5th Dutch Bio-Medical Engineering Conference, BME 2015 - Hotel Zuiderduin, Egmond aan Zee, Netherlands Duration: 22 Jan 2015 → 23 Jan 2015 Conference number: 5

Conference

Conference	5th Dutch Bio-Medical Engineering Conference, BME 2015
Abbreviated title	BME 2015
Country/Territory	Netherlands
City	Egmond aan Zee
Period	22/01/15 → 23/01/15

Keywords

BSS-Central mechanisms underlying chronic pain
Nociception
Electrical stimulation
Pain
Psychophysics
Human subjects

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@inproceedings{33128eb1174f4741b032660ea6c3e87d,

title = "Nociceptive detection probability depends on the temporal properties of electrocutaneous stimuli",

abstract = "Electrical stimulation of the skin using a needle-electrode specifically activates nociceptive nerve fibres. The detection of such stimuli by subjects depends on the activation of subsequent nociceptive mechanisms. Activation of these mechanisms depends on the temporal stimulus properties, such as the pulse-width, number of pulses, and inter-pulse interval. Here, we study whether different temporal stimulus properties do not only affect the detection threshold, but also the slope of the psychophysical curve. 30 healthy human subjects were included in a 10-minute psychophysical experiment. The results showed that the psychophysical function, and thus the detection probability, depends on stimulus properties. This suggests that additional estimation of the psychophysical curve could be useful for improved observation of (several) nociceptive mechanisms.",

keywords = "BSS-Central mechanisms underlying chronic pain, Nociception, Electrical stimulation, Pain, Psychophysics, Human subjects",

author = "Doll, {R.J. (Robert)} and Maten, {A.C.A. (Floor)} and Spaan, {S.P.G. (Sjoerd)} and Veltink, {P.H. (Peter)} and Buitenweg, {J.R. (Jan)}",

year = "2015",

language = "English",

pages = "146--146",

booktitle = "5th Dutch Conference on Bio-Medical Engineering",

publisher = "BME",

note = "5th Dutch Bio-Medical Engineering Conference, BME 2015, BME 2015 ; Conference date: 22-01-2015 Through 23-01-2015",

}

Nociceptive detection probability depends on the temporal properties of electrocutaneous stimuli. / Doll, R.J. (Robert); Maten, A.C.A. (Floor); Spaan, S.P.G. (Sjoerd); Veltink, P.H. (Peter); Buitenweg, J.R. (Jan).

5th Dutch Conference on Bio-Medical Engineering. Egmond aan Zee, The Netherlands : BME, 2015. p. 146-146.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Academic

TY - GEN

T1 - Nociceptive detection probability depends on the temporal properties of electrocutaneous stimuli

AU - Doll, R.J. (Robert)

AU - Maten, A.C.A. (Floor)

AU - Spaan, S.P.G. (Sjoerd)

AU - Veltink, P.H. (Peter)

AU - Buitenweg, J.R. (Jan)

N1 - Conference code: 5

PY - 2015

Y1 - 2015

N2 - Electrical stimulation of the skin using a needle-electrode specifically activates nociceptive nerve fibres. The detection of such stimuli by subjects depends on the activation of subsequent nociceptive mechanisms. Activation of these mechanisms depends on the temporal stimulus properties, such as the pulse-width, number of pulses, and inter-pulse interval. Here, we study whether different temporal stimulus properties do not only affect the detection threshold, but also the slope of the psychophysical curve. 30 healthy human subjects were included in a 10-minute psychophysical experiment. The results showed that the psychophysical function, and thus the detection probability, depends on stimulus properties. This suggests that additional estimation of the psychophysical curve could be useful for improved observation of (several) nociceptive mechanisms.

AB - Electrical stimulation of the skin using a needle-electrode specifically activates nociceptive nerve fibres. The detection of such stimuli by subjects depends on the activation of subsequent nociceptive mechanisms. Activation of these mechanisms depends on the temporal stimulus properties, such as the pulse-width, number of pulses, and inter-pulse interval. Here, we study whether different temporal stimulus properties do not only affect the detection threshold, but also the slope of the psychophysical curve. 30 healthy human subjects were included in a 10-minute psychophysical experiment. The results showed that the psychophysical function, and thus the detection probability, depends on stimulus properties. This suggests that additional estimation of the psychophysical curve could be useful for improved observation of (several) nociceptive mechanisms.

KW - BSS-Central mechanisms underlying chronic pain

KW - Nociception

KW - Electrical stimulation

KW - Pain

KW - Psychophysics

KW - Human subjects

M3 - Conference contribution

SP - 146

EP - 146

BT - 5th Dutch Conference on Bio-Medical Engineering

PB - BME

CY - Egmond aan Zee, The Netherlands

T2 - 5th Dutch Bio-Medical Engineering Conference, BME 2015

Y2 - 22 January 2015 through 23 January 2015

ER -

Nociceptive detection probability depends on the temporal properties of electrocutaneous stimuli

Abstract

Conference

Keywords

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